SCHEMBL2346090

SCHEMBL2346090

C=CCc1cccc(C=C(C(=O)O)C(=O)O)c1CC=C

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GABRA1 P14867 2/20 0.41
▸ GABRB2 P47870 2/20 0.41
▸ KDM4E B2RXH2 5/20 0.38
▸ MEN1 O00255 4/20 0.38
▸ KMT2A Q03164 4/20 0.38
▸ LMNA P02545 2/20 0.38
▸ MAPT P10636 2/20 0.38
▸ HTT P42858 2/20 0.38
▸ ALOX12 P18054 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ AKR1B1 P15121 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ MTNR1A P48039 1/20 0.36
▸ TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7026654 0.78 PTGER3 (0.50) GABRA1GABRB2KDM4EMAPTHTT
SCHEMBL2141001 0.76 GABRA1 (0.44) GABRA1GABRB2KDM4EMEN1KMT2A
SCHEMBL7219053 0.76 GABRA1 (0.47) GABRA1GABRB2KDM4EMEN1KMT2A
SCHEMBL345322 0.76 KDM4E (0.40) GABRA1GABRB2KDM4EMEN1KMT2A
SCHEMBL28730777 0.74 LMNA (0.50) LMNAMAPT
SCHEMBL2361001 0.73 GABRA1 (0.46) GABRA1GABRB2KDM4EMEN1KMT2A
SCHEMBL18136 0.73 GABRA1 (0.56) GABRA1GABRB2KDM4EMEN1KMT2A
SCHEMBL21462042 0.73 GABRA1 (0.48) GABRA1GABRB2KDM4EMEN1KMT2A
SCHEMBL5683687 0.71 GABRA1 (0.43) GABRA1GABRB2KDM4EKMT2AALDH1A1
SCHEMBL3297839 0.71 NFE2L2 (0.42) GABRA1GABRB2KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080131381-A1 METHODS FOR PHOTOSTABILIZING INGREDIENTS WITHIN COSMETICS, PERSONAL CARE AND HOUSEHOLD PRODUCTS AND COMPOSITIONS OBTAINED THEREFROM MERCK PATENT GESELLSCHAFT (DE) 2008-06-05 — — US claimed
US-5670140-A SKIN PROTECTION FOR COSMETICS FOR RADIATION RESISTANCE L'OREAL (FR) 1997-09-23 — — US claimed
US-5624663-A Photostable cosmetic filter composition cotaining a UV-A filter and a substituted dialkylbenzalmalonate, the use of substituted dialkylbenzalmalonates in cosmetics as broad-band solar filters and novel substituted dialkyl malonates L'OREAL (FR) 1997-04-29 — — US claimed
EP-0551510-B1 PHOTOSTABLE FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND A 4-METHOXY BENZYLIDENE CYANOACETATE OREAL (FR) 1995-09-27 — — EP claimed
EP-0601080-B1 FILTERING COSMETIC COMPOSITION CONTAINING A LIPOSOLUBLE FILTER POLYMER WITH HYDROCARBONATED STRUCTURE AND A FILTER SILICONE OREAL (FR) 1995-07-26 — — EP claimed
EP-0551510-A1 PHOTOSTABLE FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND A 4-METHOXY BENZYLIDENE CYANOACETATE. OREAL (FR) 1993-07-21 — — EP claimed
WO-1993002659-A1 PHOTOSTABLE FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND A 4-METHOXY BENZYLIDENE CYANOACETATE L'OREAL (FR) 1993-02-18 — — WO claimed
US-12011496-B2 Topical macqui berry formulation Tracie Martyn International, Inc. (US) 2024-06-18 — — US disclosed
US-10993897-B2 Topical macqui berry formula Tracie Martyn International, Inc. (US) 2021-05-04 — — US disclosed
US-20190151227-A1 TOPICAL MACQUI BERRY FORMULA TRACIE MARTYN INT INC (US) 2019-05-23 — — US disclosed
EP-2451427-B1 UV FILTER COMBINATIONS COMPRISING BENZYLIDENE MALONATES BASF SE (DE) 2018-04-25 — — EP disclosed
US-20170027853-A1 TOPICAL MACQUI BERRY FORMULATION TRACIE MARTYN INTERNATIONAL, LLC 2017-02-02 — — US disclosed
US-9463153-B2 Topical macqui berry formulation Trade Martyn International, LLC (US) 2016-10-11 — — US disclosed
US-5670140-A SKIN PROTECTION FOR COSMETICS FOR RADIATION RESISTANCE L'OREAL (FR) 1997-09-23 — — US disclosed
US-5670140-A SKIN PROTECTION FOR COSMETICS FOR RADIATION RESISTANCE L'OREAL (FR) 1997-09-23 — — US disclosed
US-5670140-A SKIN PROTECTION FOR COSMETICS FOR RADIATION RESISTANCE L'OREAL (FR) 1997-09-23 — — US disclosed
US-5624663-A Photostable cosmetic filter composition cotaining a UV-A filter and a substituted dialkylbenzalmalonate, the use of substituted dialkylbenzalmalonates in cosmetics as broad-band solar filters and novel substituted dialkyl malonates L'OREAL (FR) 1997-04-29 — — US disclosed
US-5624663-A Photostable cosmetic filter composition cotaining a UV-A filter and a substituted dialkylbenzalmalonate, the use of substituted dialkylbenzalmalonates in cosmetics as broad-band solar filters and novel substituted dialkyl malonates L'OREAL (FR) 1997-04-29 — — US disclosed
US-5624663-A Photostable cosmetic filter composition cotaining a UV-A filter and a substituted dialkylbenzalmalonate, the use of substituted dialkylbenzalmalonates in cosmetics as broad-band solar filters and novel substituted dialkyl malonates L'OREAL (FR) 1997-04-29 — — US disclosed
EP-0551510-B1 PHOTOSTABLE FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND A 4-METHOXY BENZYLIDENE CYANOACETATE OREAL (FR) 1995-09-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080131381-A1 METHODS FOR PHOTOSTABILIZING INGREDIENTS WITHIN COSMETICS, PERSONAL CARE AND HOUSEHOLD PRODUCTS AND COMPOSITIONS OBTAINED THEREFROM TYR, NISCH, PPOX GABRA1 4387/4885GABRB2 4689/4885KDM4E 2860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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