Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 1/20 | 1.00 |
| ▸ | RELA | Q04206 | 1/20 | 1.00 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.63 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | PPARG | P37231 | 2/20 | 0.62 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.56 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.53 |
| ▸ | GAPDH | P04406 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1480564 | 1.00 | FPR2 (1.00) | FPR2NFKB1NFKB2RELALTB4R2 | |
| SCHEMBL1692159 | 1.00 | FPR2 (1.00) | FPR2NFKB1NFKB2RELALTB4R2 | |
| Lipoxin A4 SCHEMBL19668574 | 1.00 | FPR2 (1.00) | FPR2NFKB1NFKB2RELALTB4R2 | |
| SCHEMBL3299698 | 1.00 | FPR2 (1.00) | FPR2NFKB1NFKB2RELALTB4R2 | |
| Lipoxin A4 SCHEMBL3302874 | 1.00 | FPR2 (1.00) | FPR2NFKB1NFKB2RELALTB4R2 | |
| Lipoxin A4 SCHEMBL1691709 | 1.00 | FPR2 (1.00) | FPR2NFKB1NFKB2RELALTB4R2 | |
| SCHEMBL12102087 | 1.00 | FPR2 (1.00) | FPR2NFKB1NFKB2RELALTB4R2 | |
| Lipoxin A4 SCHEMBL3408493 | 1.00 | FPR2 (1.00) | FPR2NFKB1NFKB2RELALTB4R2 | |
| Lipoxin A4 SCHEMBL8743448 | 1.00 | FPR2 (1.00) | FPR2NFKB1NFKB2RELALTB4R2 | |
| SCHEMBL5162003 | 1.00 | FPR2 (1.00) | FPR2NFKB1NFKB2RELALTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722654-B2 | Lipoxin analogs as novel inhibitors of angiogenesis | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-8008282-B2 | Lipoxin analogs as novel inhibitors of angiogenesis | THE BRIGHAM & WOMEN'S HOSPITAL, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-20080064749-A1 | Lipoxin Analogs as Novel Inhibitors of Angiogenesis | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2008-03-13 | — | — | US | disclosed |
| US-20060009521-A1 | Lipoxin analogs as novel inhibitors of angiogenesis | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064749-A1 | Lipoxin Analogs as Novel Inhibitors of Angiogenesis | ALOX5, ALOX15B, ALOX15 | FPR2 137/4885NFKB1 868/4885NFKB2 1745/4885 |
| US-20060009521-A1 | Lipoxin analogs as novel inhibitors of angiogenesis | ALOX5, ALOX15B, ALOX15 | FPR2 137/4885NFKB1 868/4885NFKB2 1745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.