Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16172610 | 0.78 | SLC5A1 (0.34) | PGR | |
| SCHEMBL18474236 | 0.76 | PGR (0.45) | PGR | |
| SCHEMBL9727613 | 0.76 | OPRM1 (0.41) | — | |
| SCHEMBL309789 | 0.76 | KDM1A (0.36) | PGR | |
| SCHEMBL12680664 | 0.73 | ALDH1A1 (0.35) | PGR | |
| SCHEMBL17591368 | 0.73 | DRD2 (0.39) | — | |
| SCHEMBL15147627 | 0.72 | KDM1A (0.41) | PGR | |
| SCHEMBL309301 | 0.72 | ALDH1A1 (0.38) | PGR | |
| SCHEMBL24822914 | 0.71 | HTT (0.32) | PGR | |
| SCHEMBL23714893 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3827830-A1 | COMBINATIONS COMPRISING POSITIVE ALLOSTERIC MODULATORS OR ORTHOSTERIC AGONISTS OF METABOTROPIC GLUTAMATERGIC RECEPTOR SUBTYPE 2 AND THEIR USE | Janssen Pharmaceutica NV (BE) | 2021-06-02 | — | — | EP | disclosed |