Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27009265 | 0.86 | GABRP (0.43) | CHRNB2CHRNA4CHRNB4LMNASLC15A2 | |
| SCHEMBL23463503 | 0.84 | ALDH1A1 (0.33) | ALDH1A1CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL20104586 | 0.84 | ALOX15 (0.36) | CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL19546492 | 0.80 | ALDH1A1 (0.41) | ALDH1A1CHRNB2CHRNA4CHRNB4CHRM1 | |
| SCHEMBL23463665 | 0.78 | CHRNB2 (0.41) | ALDH1A1CHRNB2CHRNA4CHRNB4CHRM1 | |
| SCHEMBL27009136 | 0.76 | ALOX15 (0.32) | — | |
| SCHEMBL13267367 | 0.76 | USP2 (0.30) | — | |
| SCHEMBL23463333 | 0.75 | ALDH1A1 (0.36) | ALDH1A1CHRM1TDP1LMNASLC15A2 | |
| SCHEMBL15457551 | 0.74 | KDM4E (0.30) | — | |
| SCHEMBL22446850 | 0.73 | CHRNB2 (0.54) | ALDH1A1CHRNB2CHRNA4CHRNB4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3919080-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | Chongqing Upgra Biotechnology Co., Ltd. (CN) | 2021-12-08 | — | — | EP | disclosed |
| WO-2021103342-A1 | POLYETHYLENE GLYCOL CONJUGATED DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |