SCHEMBL234680

SCHEMBL234680

C(OCC1CO1)C1CO1.CC(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.53
ESR2 Q92731 2/20 0.53
PDCD1 Q15116 1/20 0.53
CD274 Q9NZQ7 1/20 0.53
TSHR P16473 5/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 6/20 0.37
GLA P06280 1/20 0.37
TDP1 Q9NUW8 3/20 0.36
MAPT P10636 3/20 0.36
CYP3A4 P08684 2/20 0.36
CYP1A2 P05177 2/20 0.36
LMNA P02545 1/20 0.36
PGR P06401 1/20 0.36
CHRM2 P08172 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
AR P10275 1/20 0.36
CYP2D6 P10635 1/20 0.36
CHRM1 P11229 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29184953 0.94 ESR1 (0.47) ESR1ESR2PDCD1CD274ALDH1A1
SCHEMBL28041463 0.90 ESR1 (0.39) ESR1ESR2PDCD1CD274TSHR
SCHEMBL28140186 0.86 TSHR (0.39) ESR1ESR2PDCD1CD274TSHR
SCHEMBL17386348 0.86 TSHR (0.39) ESR1ESR2PDCD1CD274TSHR
SCHEMBL16199118 0.86 ALDH1A1 (0.53) ESR1ESR2PDCD1CD274TSHR
SCHEMBL8661945 0.86 ESR1 (0.41) ESR1ESR2PDCD1CD274TSHR
Hydroquinone SCHEMBL50263 0.86 TSHR (0.48) TSHRMAPK1SMN1; SMN2ALDH1A1GLA
SCHEMBL232506 0.84 ESR1 (0.42) ESR1ESR2TSHRMAPK1SMN1; SMN2
SCHEMBL14445085 0.83 TSHR (0.38) ESR1ESR2PDCD1CD274TSHR
P-Cresol SCHEMBL3682617 0.81 ACHE (0.48) ESR2TSHRMAPK1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62124114-A None JP disclosed
JP-61036318-A None JP disclosed
JP-60069125-A None JP disclosed
CN-116057043-B Urea derivatives and their use as curing agents and curing accelerators for resin systems 赫克塞尔合成有限公司 2024-04-16 CN disclosed
US-11939421-B2 Or relating to curing agents HEXCEL COMPOSITES LIMITED (GB) 2024-03-26 US disclosed
US-11879052-B2 Curatives HEXCEL COMPOSITES LIMITED (GB) 2024-01-23 US disclosed
US-11702516-B2 Curative composition and a resin composition containing the curative composition HEXCEL COMPOSITES LIMITED (GB) 2023-07-18 US disclosed
EP-4196462-A1 UREA DERIVATIVES AND THEIR USE AS CURATIVES AND CURATIVE ACCELERATORS FOR RESIN SYSTEMS Hexcel Composites Limited (GB) 2023-06-21 EP disclosed
US-20230167272-A1 IMPROVEMENTS IN OR RELATING TO CURATIVES HEXCEL COMPOSITES LIMITED (GB) 2023-06-01 US disclosed
CN-116057043-A Urea derivatives and their use as curing agents and curing accelerators for resin systems 赫克塞尔合成有限公司 2023-05-02 CN disclosed
EP-0761722-B1 ORGANOPOLYSILOXANE DERIVATIVE NAGASE CIBA LTD (JP) 2002-06-12 EP disclosed
US-5844053-A Organo-polysiloxane derivartives NAGASE-CIBA, LTD. (JP) 1998-12-01 US disclosed
EP-0761722-A1 ORGANOPOLYSILOXANE DERIVATIVE Nagase-Ciba Ltd. (JP) 1997-03-12 EP disclosed
EP-0224391-B1 EPOXY RESIN COMPOSITIONS MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-09-04 EP disclosed
US-4929708-A MOLDING MATERIALS, IMPACT STRENGTH, HEAT RESISTANCE MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-05-29 US disclosed
JP-S62124114-A EPOXY RESIN COMPOSITION MITSUI PETROCHEM IND LTD 1987-06-05 JP disclosed
EP-0224391-A1 Epoxy resin compositions MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-06-03 EP disclosed
US-4626379-A REACTION PRODUCT OF BLEND OF POLYOXYALKYLENE OXIDE COPOLYMER AND VINYL MONOMER PETROLITE CORPORATION (US) 1986-12-02 US disclosed
JP-S6136318-A EPOXY RESIN COMPOSITION HITACHI CHEM CO LTD 1986-02-21 JP disclosed
JP-S6069125-A EPOXY RESIN COMPOSITION HITACHI CHEM CO LTD 1985-04-19 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11939421-B2 Or relating to curing agents FABP4, RARA, ADIPOR1 ESR1 1730/4885ESR2 1873/4885PDCD1 1193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.