SCHEMBL2347014

SCHEMBL2347014

O=C(O)c1nc(Cl)cc(Cl)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
LMNA P02545 1/20 0.43
GRIK1 P39086 1/20 0.43
GRIA1 P42261 1/20 0.43
GRIA2 P42262 1/20 0.43
GRIA3 P42263 1/20 0.43
GRIA4 P48058 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIK2 Q13002 1/20 0.43
GRIK3 Q13003 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIK4 Q16099 1/20 0.43
GRIK5 Q16478 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21120426 0.81 ALDH1A1 (0.46) TDP1GRIN2DGRIN3BLMNAGRIK1
SCHEMBL8511633 0.81 TTR (0.48) TDP1GRIN2DGRIN3BLMNAGRIK1
SCHEMBL536122 0.79 TDP1 (0.46) TDP1GRIN2DGRIN3BLMNAGRIK1
SCHEMBL14768691 0.79 MEN1 (0.40) TDP1GRIN2DGRIN3BLMNAGRIK1
SCHEMBL15032599 0.79 ALDH1A1 (0.48) TDP1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL29390992 0.79 TDP1 (0.50) TDP1GRIN2DGRIN3BLMNAGRIK1
SCHEMBL116082 0.79 TDP1 (0.50) TDP1GRIN2DGRIN3BLMNAGRIK1
SCHEMBL5808658 0.79 TDP1 (0.41) TDP1GRIN2DGRIN3BLMNAGRIK1
SCHEMBL3218994 0.79 TDP1 (0.50) TDP1GRIN2DGRIN3BLMNAGRIK1
SCHEMBL1404403 0.78 TDP1 (0.48) TDP1GRIN2DGRIN3BLMNAGRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106279012-B A kind of preparation method of 3,4,6- trichloropyridine -2- formic acid and its ester 利尔化学股份有限公司 2019-04-09 CN claimed
CN-106279012-A A kind of 3,4,6-trichloropyridine-2-formic acid and the preparation method of ester thereof 利尔化学股份有限公司 2017-01-04 CN claimed
CN-106146393-A Prepare 3,4,6-trichloropyridine-2-formic acid and the method for corresponding esters thereof 利尔化学股份有限公司 2016-11-23 CN claimed
US-4497697-A REDUCTION OF TETRACHLOROPICOLINIC ACID IN A BASIC SOLUTION THE DOW CHEMICAL COMPANY (US) 1985-02-05 US claimed
CN-106279012-B A kind of preparation method of 3,4,6- trichloropyridine -2- formic acid and its ester 利尔化学股份有限公司 2019-04-09 CN disclosed
CN-106279012-B A kind of preparation method of 3,4,6- trichloropyridine -2- formic acid and its ester 利尔化学股份有限公司 2019-04-09 CN disclosed
CN-106279012-B A kind of preparation method of 3,4,6- trichloropyridine -2- formic acid and its ester 利尔化学股份有限公司 2019-04-09 CN disclosed
CN-104066718-B Substituted benzene compounds EPIZYME股份有限公司 2017-08-29 CN disclosed
CN-106279012-A A kind of 3,4,6-trichloropyridine-2-formic acid and the preparation method of ester thereof 利尔化学股份有限公司 2017-01-04 CN disclosed
CN-106279012-A A kind of 3,4,6-trichloropyridine-2-formic acid and the preparation method of ester thereof 利尔化学股份有限公司 2017-01-04 CN disclosed
CN-106279012-A A kind of 3,4,6-trichloropyridine-2-formic acid and the preparation method of ester thereof 利尔化学股份有限公司 2017-01-04 CN disclosed
CN-106146393-A Prepare 3,4,6-trichloropyridine-2-formic acid and the method for corresponding esters thereof 利尔化学股份有限公司 2016-11-23 CN disclosed
EP-1246802-A1 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES Dow Agrosciences LLC (US) 2002-10-09 EP disclosed
US-20010047099-A1 4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC 2001-11-29 US disclosed
US-6297197-B1 DEMONSTRATING A BROAD SPECTRUM OF WEED CONTROL. DOW AGROSCIENCES LLC 2001-10-02 US disclosed
WO-2001051468-A1 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2001-07-19 WO disclosed
US-4497697-A REDUCTION OF TETRACHLOROPICOLINIC ACID IN A BASIC SOLUTION THE DOW CHEMICAL COMPANY (US) 1985-02-05 US disclosed
EP-0023077-B1 ELECTROLYTIC PRODUCTION OF CERTAIN TRICHLOROPICOLINIC ACIDS AND/OR 3,6-DICHLOROPICOLINIC ACID THE DOW CHEMICAL COMPANY (US) 1984-06-20 EP disclosed
EP-0023077-A2 Electrolytic production of certain trichloropicolinic acids and/or 3,6-dichloropicolinic acid THE DOW CHEMICAL COMPANY (US) 1981-01-28 EP disclosed
US-4217185-A Electrolytic production of certain trichloropicolinic acids and/or 3,6-dichloropicolinic acid THE DOW CHEMICAL COMPANY (US) 1980-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010047099-A1 4-aminopicolinates and their use as herbicides AADAT, ABAT, DDT TDP1 3400/4885GRIN2D 232/4885GRIN3B 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.