Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 7/20 | 0.45 |
| ▸ | ABL1 | P00519 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20219716 | 1.00 | SRC (0.45) | SRCABL1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL23472165 | 0.81 | TLR8 (0.51) | TLR8TLR7L3MBTL1 | |
| SCHEMBL20219399 | 0.81 | TLR8 (0.51) | TLR8TLR7L3MBTL1 | |
| SCHEMBL23472353 | 0.78 | NPSR1 (0.39) | SRCABL1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL23472685 | 0.78 | TLR8 (0.49) | LMNASMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL23472330 | 0.77 | TLR8 (0.47) | TLR8TLR7L3MBTL1 | |
| SCHEMBL20219506 | 0.77 | SRC (0.44) | SRCABL1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20219480 | 0.74 | LMNA (0.45) | SRCABL1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL23472180 | 0.72 | ALDH1A1 (0.43) | LMNASMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL23472202 | 0.71 | CYP1A2 (0.51) | LMNASMN1; SMN2ALDH1A1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |