Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472223 | 0.83 | TRPM8 (0.45) | TRPM8MITFLMNAMAPTSMN1; SMN2 | |
| SCHEMBL23472142 | 0.82 | TRPM8 (0.44) | TRPM8MITFLMNAMAPTSMN1; SMN2 | |
| SCHEMBL15470343 | 0.82 | TRPM8 (0.44) | TRPM8MITFLMNAMAPTSMN1; SMN2 | |
| SCHEMBL19274227 | 0.82 | TRPM8 (0.44) | TRPM8MITFLMNAMAPTSMN1; SMN2 | |
| SCHEMBL20219550 | 0.75 | CXCR2 (0.38) | TRPM8MITFLMNAMAPTSMN1; SMN2 | |
| SCHEMBL20219573 | 0.74 | TLR7 (0.35) | TRPM8MITFLMNAMAPTSMN1; SMN2 | |
| SCHEMBL23472645 | 0.72 | TRPM8 (0.40) | TRPM8MITFLMNAMAPTSMN1; SMN2 | |
| SCHEMBL20219325 | 0.72 | TRPM8 (0.40) | TRPM8MITFLMNAMAPTSMN1; SMN2 | |
| SCHEMBL13195755 | 0.72 | TRPM8 (0.40) | TRPM8MITFLMNAMAPTSMN1; SMN2 | |
| SCHEMBL23472112 | 0.71 | TLR7 (0.34) | TRPM8MITFLMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |