Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472112 | 0.86 | TLR7 (0.34) | TLR7TLR8TRPM8KCNH2MITF | |
| SCHEMBL20413303 | 0.85 | TLR7 (0.37) | TLR7TLR8TRPM8KCNH2MITF | |
| SCHEMBL20219539 | 0.84 | TLR7 (0.46) | TLR7TLR8KCNH2 | |
| SCHEMBL13195109 | 0.84 | TLR7 (0.46) | TLR7TLR8KCNH2 | |
| SCHEMBL23472637 | 0.83 | STK17A (0.30) | TRPM8 | |
| SCHEMBL20219550 | 0.79 | CXCR2 (0.38) | TRPM8MITFLMNAMAPTSMN1; SMN2 | |
| SCHEMBL23472188 | 0.79 | TLR7 (0.36) | TLR7TLR8KCNH2LMNA | |
| SCHEMBL23472590 | 0.77 | STK17A (0.31) | — | |
| SCHEMBL23472496 | 0.76 | TLR7 (0.39) | TLR7TLR8KCNH2 | |
| SCHEMBL23472468 | 0.74 | TRPM8 (0.42) | TRPM8MITFLMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |
| EP-3330257-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | Janssen Sciences Ireland UC (IE) | 2018-06-06 | — | — | EP | disclosed |