Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 3/20 | 0.36 |
| ▸ | AXL | P30530 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15469955 | 0.83 | CYP1A2 (0.55) | CYP1A2CYP2D6CYP3A4TLR8TLR7 | |
| SCHEMBL23472599 | 0.78 | CYP1A2 (0.44) | CYP1A2CYP2D6CYP3A4TLR8TLR7 | |
| SCHEMBL20219314 | 0.78 | CYP1A2 (0.39) | CYP1A2CYP2D6CYP3A4TLR8TLR7 | |
| SCHEMBL20219466 | 0.78 | TLR7 (0.42) | CYP1A2CYP2D6CYP3A4TLR8TLR7 | |
| SCHEMBL20219444 | 0.77 | TLR7 (0.42) | CYP1A2CYP3A4TLR8TLR7MERTK | |
| SCHEMBL20219428 | 0.77 | TLR7 (0.40) | CYP1A2CYP2D6CYP3A4TLR8TLR7 | |
| SCHEMBL23472603 | 0.76 | TLR8 (0.36) | TLR8TLR7MERTKAXLTYRO3 | |
| SCHEMBL23472423 | 0.76 | MEN1 (0.45) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL20219264 | 0.76 | GCK (0.42) | CYP1A2CYP2D6CYP3A4TLR8TLR7 | |
| SCHEMBL23472434 | 0.76 | CYP2D6 (0.40) | CYP1A2CYP2D6CYP3A4TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |