Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | TERT | O14746 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21647159 | 0.88 | APP (0.42) | ALDH1A1HTTSMN1; SMN2THRBNPSR1 | |
| SCHEMBL23473363 | 0.74 | CDK2 (0.38) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL23473389 | 0.68 | CDK2 (0.44) | ALDH1A1SMN1; SMN2KDM4EHPGDHSD17B10 | |
| SCHEMBL21647175 | 0.67 | TERT (0.60) | ALDH1A1SMN1; SMN2KDM4EHPGDHSD17B10 | |
| SCHEMBL23473325 | 0.65 | TERT (0.44) | ALDH1A1HTTSMN1; SMN2THRBNPSR1 | |
| SCHEMBL23473424 | 0.65 | USP8 (0.56) | ALDH1A1SMN1; SMN2KDM4EHPGDHSD17B10 | |
| SCHEMBL21668590 | 0.64 | CDK2 (0.54) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL21668591 | 0.62 | CDK2 (0.40) | KDM4ECDK2GAAAPPMAPT | |
| SCHEMBL23473366 | 0.62 | TERT (0.45) | ALDH1A1SMN1; SMN2KDM4EHPGDHSD17B10 | |
| SCHEMBL21647180 | 0.62 | TERT (0.62) | KDM4ECDK2GAAAPPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831821-A1 | COMPOUND FOR TREATING NERVOUS SYSTEM DISEASES AND USE THEREOF | Shaanxi Micot Technology Limited Company (CN) | 2021-06-09 | — | — | EP | disclosed |