Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21668590 | 0.82 | CDK2 (0.54) | CDK2ABCG2CDK1MEN1KMT2A | |
| SCHEMBL21668603 | 0.77 | ABCG2 (0.49) | CDK2ABCG2MEN1CYP3A4KMT2A | |
| SCHEMBL14697003 | 0.76 | ABCG2 (0.69) | CDK2ABCG2MEN1CYP3A4KMT2A | |
| SCHEMBL21668602 | 0.75 | ABCG2 (0.47) | CDK2ABCG2MEN1CYP3A4KMT2A | |
| SCHEMBL23473363 | 0.74 | CDK2 (0.38) | CDK2ABCG2CDK1MEN1KMT2A | |
| SCHEMBL22789251 | 0.72 | TERT (0.44) | CDK2CDK1KDM4EMAPTIP6K1 | |
| SCHEMBL21647180 | 0.72 | TERT (0.62) | CDK2CDK1KDM4EMAPTIP6K1 | |
| SCHEMBL14697006 | 0.69 | CDK2 (0.48) | CDK2MEN1CYP3A4KMT2AHSD17B10 | |
| SCHEMBL23473440 | 0.68 | TERT (0.40) | CDK2CDK1MEN1KMT2AHSD17B10 | |
| SCHEMBL23473355 | 0.68 | ALDH1A1 (0.35) | CDK2MEN1KMT2AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831821-A1 | COMPOUND FOR TREATING NERVOUS SYSTEM DISEASES AND USE THEREOF | Shaanxi Micot Technology Limited Company (CN) | 2021-06-09 | — | — | EP | disclosed |