SCHEMBL23476147

SCHEMBL23476147

CCC(=O)NCCNC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.52
RECQL P46063 1/20 0.50
KIF11 P52732 1/20 0.49
MTNR1A P48039 5/20 0.47
MTNR1B P49286 5/20 0.47
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12974349 0.83 EPHX2 (0.55) MTNR1AMEN1KMT2AHPGD
SCHEMBL13659424 0.78 LMNA (0.57) RECQLKIF11KMT2AHPGDRAB9A
SCHEMBL31505697 0.78 MALT1 (0.51) KCNN4KIF11MEN1KMT2AGAA
SCHEMBL12264131 0.78 KIF11 (0.74) KCNN4KIF11MEN1KMT2AALDH1A1
SCHEMBL12914773 0.77 KCNN4 (0.50) KCNN4RECQLMTNR1AMTNR1BALDH1A1
SCHEMBL17875119 0.77 KIF11 (0.44) KCNN4KIF11KMT2AALDH1A1HPGD
SCHEMBL17164962 0.75 LMNA (0.51) KIF11KMT2AALDH1A1HPGDTSHR
SCHEMBL17916522 0.75 HDAC3 (0.51) KCNN4KIF11KMT2AHPGDRAB9A
Acetic Acid SCHEMBL23711260 0.75 KCNN4 (0.53) KCNN4KIF11ALDH1A1HPGDTSHR
SCHEMBL23561546 0.74 TAAR1 (0.48) KIF11RAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210169919-A1 EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY SAREPTA THERAPEUTICS, INC. (US) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210169919-A1 EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY UTRN, SMN1; SMN2, DCLRE1B KCNN4 3840/4885RECQL 2647/4885KIF11 643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.