SCHEMBL23477181

SCHEMBL23477181

COP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)[C@H](O)[C@@H]1OP(=O)(O)OC[C@@H]1C[C@@H](O)[C@H](n2ccc(=O)[nH]c2=O)O1

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 7/20 0.65
▸ P2RY4 P51582 5/20 0.65
▸ P2RY6 Q15077 3/20 0.65
▸ F2 P00734 1/20 0.61
▸ RNASEL Q05823 4/20 0.56
▸ FUT5 Q11128 1/20 0.54
▸ TGM2 P21980 1/20 0.53
▸ NT5E P21589 1/20 0.51
▸ P2RY14 Q15391 2/20 0.49
▸ KRAS P01116 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25552773 0.93 TGM2 (0.60) P2RY2P2RY4P2RY6F2RNASEL
SCHEMBL23477443 0.91 FUT5 (0.54) P2RY2P2RY4P2RY6F2RNASEL
SCHEMBL23477028 0.90 FUT5 (0.58) P2RY2P2RY4P2RY6F2RNASEL
SCHEMBL24771772 0.89 RNASEL (0.56) RNASELFUT5TGM2
SCHEMBL23477159 0.89 RNASEL (0.56) RNASELFUT5TGM2
SCHEMBL19448916 0.88 TGM2 (0.61) P2RY2P2RY4P2RY6RNASELFUT5
SCHEMBL21648046 0.88 TGM2 (0.61) P2RY2P2RY4P2RY6RNASELFUT5
SCHEMBL23477132 0.87 FUT5 (0.60) P2RY2P2RY4P2RY6F2RNASEL
SCHEMBL29589660 0.86 P2RY2 (0.66) P2RY2P2RY4P2RY6F2RNASEL
SCHEMBL20762956 0.85 TGM2 (0.65) P2RY2P2RY4P2RY6RNASELFUT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170043-A1 DC-SIGN ANTIBODY CONJUGATES COMPRISING STING AGONISTS CHINOOK THERAPEUTICS, INC. 2021-06-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170043-A1 DC-SIGN ANTIBODY CONJUGATES COMPRISING STING AGONISTS STING1, TLR9, TLR3 P2RY2 1477/4885P2RY4 1086/4885P2RY6 1696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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