Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 8/20 | 0.36 |
| ▸ | CTSL | P07711 | 5/20 | 0.34 |
| ▸ | CTSB | P07858 | 5/20 | 0.34 |
| ▸ | CTSH | P09668 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564282 | 0.98 | CYP1A2 (0.34) | CYP1A2METAP1KDM4EMEN1USP2 | |
| Methylamine SCHEMBL27815959 | 0.86 | TSHR (0.31) | MAPT | |
| SCHEMBL9921964 | 0.83 | TSHR (0.38) | CYP1A2METAP1KDM4EMEN1USP2 | |
| SCHEMBL9921746 | 0.78 | CTSK (0.42) | CTSKCTSLCTSBCTSH | |
| SCHEMBL9921684 | 0.78 | CTSK (0.42) | CTSKCTSLCTSBCTSH | |
| SCHEMBL28122487 | 0.75 | CYP1A2 (0.43) | CYP1A2METAP1MEN1KMT2ACTSK | |
| SCHEMBL7634653 | 0.75 | CYP1A2 (0.48) | CYP1A2METAP1SIGMAR1 | |
| SCHEMBL19383239 | 0.74 | CYP1A2 (0.41) | CYP1A2METAP1SIGMAR1 | |
| SCHEMBL29102100 | 0.74 | METAP1 (0.44) | CYP1A2METAP1HPGDSIGMAR1 | |
| SCHEMBL9918279 | 0.73 | TSHR (0.35) | CYP1A2METAP1KDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963194-A1 | NITRILE PERFUMERY MATERIAL | Bush Boake Allen Inc. (US) | 1999-12-15 | — | — | EP | claimed |
| WO-1999026601-A1 | NITRILE PERFUMERY MATERIAL | BUSH BOAKE ALLEN INC. (US) | 1999-06-03 | — | — | WO | claimed |
| US-5888962-A | CONTAINING 3-METHYL-5-(PHENYL OR CYCLOHEXYL)-PENTANENITRILE | BUSH BOAKE ALLEN INC. (US) | 1999-03-30 | — | — | US | claimed |
| US-10426131-B2 | Fragrance composition | GIVAUDAN S.A. (CH) | 2019-10-01 | — | — | US | disclosed |
| US-10004205-B2 | Fragrance composition | GIVAUDAN SA (CH) | 2018-06-26 | — | — | US | disclosed |
| US-20180070555-A1 | Fragrance Composition | GIVAUDAN S.A. (CH) | 2018-03-15 | — | — | US | disclosed |
| EP-2940005-B1 | NITRILE COMPOUND, METHOD OF PREPARATION THEREOF AND FRAGRANCE COMPOSITION COMPRISING THE NITRILE COMPOUND | KAO CORP (JP) | 2017-04-05 | — | — | EP | disclosed |
| CN-104884431-B | Nitrile compound | KAO CORP. (JP) | 2016-11-30 | — | — | CN | disclosed |
| US-9447362-B2 | Nitrile compound | KAO CORPORATION (JP) | 2016-09-20 | — | — | US | disclosed |
| US-20150353480-A1 | NITRILE COMPOUND | KAO CORPORATION (JP) | 2015-12-10 | — | — | US | disclosed |
| EP-2940005-A1 | NITRILE COMPOUND | Kao Corporation (JP) | 2015-11-04 | — | — | EP | disclosed |
| EP-1167507-A2 | Malodor counteractant compositions and methods for preparing and using same | Bush Boake Allen Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6172016-B1 | Fragrance materials | BUSH BOAKES ALLEN INC. | 2001-01-09 | — | — | US | disclosed |
| EP-0963194-A1 | NITRILE PERFUMERY MATERIAL | Bush Boake Allen Inc. (US) | 1999-12-15 | — | — | EP | disclosed |
| EP-0963194-A1 | NITRILE PERFUMERY MATERIAL | Bush Boake Allen Inc. (US) | 1999-12-15 | — | — | EP | disclosed |
| WO-1999026601-A1 | NITRILE PERFUMERY MATERIAL | BUSH BOAKE ALLEN INC. (US) | 1999-06-03 | — | — | WO | disclosed |
| WO-1999026601-A1 | NITRILE PERFUMERY MATERIAL | BUSH BOAKE ALLEN INC. (US) | 1999-06-03 | — | — | WO | disclosed |
| US-5888962-A | CONTAINING 3-METHYL-5-(PHENYL OR CYCLOHEXYL)-PENTANENITRILE | BUSH BOAKE ALLEN INC. (US) | 1999-03-30 | — | — | US | disclosed |
| US-5888962-A | CONTAINING 3-METHYL-5-(PHENYL OR CYCLOHEXYL)-PENTANENITRILE | BUSH BOAKE ALLEN INC. (US) | 1999-03-30 | — | — | US | disclosed |
| US-4193934-A | PERFUMES | HAARMANN & REIMER GMBH (DE) | 1980-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353480-A1 | NITRILE COMPOUND | NOS1, NOS2, NOS3 | CYP1A2 60/4885METAP1 4357/4885KDM4E 3401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.