Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.62 |
| ▸ | NPY1R | P25929 | 1/20 | 0.62 |
| ▸ | NPY2R | P49146 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22289498 | 0.80 | MAPT (1.00) | ALDH1A1HPGDLMNANPSR1L3MBTL1 | |
| SCHEMBL6815734 | 0.76 | ALDH1A1 (0.77) | ALDH1A1HPGDLMNAMAPTMEN1 | |
| SCHEMBL14433945 | 0.76 | ALDH1A1 (0.70) | ALDH1A1HPGDLMNAMAPTMEN1 | |
| SCHEMBL11642147 | 0.76 | MAPT (0.79) | ALDH1A1HPGDLMNANPSR1L3MBTL1 | |
| SCHEMBL7640817 | 0.76 | ALDH1A1 (0.73) | ALDH1A1HPGDLMNAMAPTMEN1 | |
| SCHEMBL6077972 | 0.75 | SMN1; SMN2 (0.58) | ALDH1A1HPGDLMNAMAPTMEN1 | |
| SCHEMBL10220635 | 0.75 | CCR2 (0.74) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL26485834 | 0.74 | LMNA (0.71) | ALDH1A1HPGDLMNANPSR1L3MBTL1 | |
| SCHEMBL26491226 | 0.74 | MAPT (1.00) | ALDH1A1HPGDLMNANPSR1L3MBTL1 | |
| SCHEMBL26491103 | 0.74 | MAPT (0.77) | ALDH1A1HPGDLMNANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642647-B2 | N1-benzo[1,3]dioxol-5-ylmethyl-N2-substituted biguanide derivative, preparation method thereof, and pharmaceutical composition containing same | HANALL BIOPHARMA CO., LTD. (KR) | 2014-02-04 | — | — | US | disclosed |
| US-20110207810-A1 | N1-BENZO[1,3]DIOXOL-5-YLMETHYL-N2-SUBSTITUTED BIGUANIDE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | HANALL BIOPHARMA CO., LTD. (KR) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207810-A1 | N1-BENZO[1,3]DIOXOL-5-YLMETHYL-N2-SUBSTITUTED BIGUANIDE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | BRCA1, TP53, SLC5A1 | ALDH1A1 1560/4885HPGD 3296/4885LMNA 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.