Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20858268 | 0.78 | SIGMAR1 (0.44) | EBPSIGMAR1 | |
| SCHEMBL20878487 | 0.78 | SIGMAR1 (0.44) | EBPSIGMAR1 | |
| SCHEMBL18568131 | 0.78 | ALDH1A1 (0.48) | SIGMAR1LTA4H | |
| SCHEMBL18567964 | 0.78 | ALDH1A1 (0.48) | SIGMAR1LTA4H | |
| SCHEMBL21120538 | 0.78 | ALDH1A1 (0.48) | SIGMAR1LTA4H | |
| SCHEMBL18568134 | 0.78 | ALDH1A1 (0.48) | SIGMAR1LTA4H | |
| SCHEMBL21348719 | 0.75 | LTA4H (0.51) | DNM1SIGMAR1LTA4H | |
| SCHEMBL25643068 | 0.75 | ADCY10 (0.30) | — | |
| SCHEMBL20333177 | 0.74 | NPC1 (0.42) | DNM1LTA4H | |
| SCHEMBL22861410 | 0.74 | ADCY10 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667652-B2 | MCL1 inhibitors | GILEAD SCIENCES, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-20210171543-A1 | MCL1 INHIBITORS | GILEAD SCIENCES, INC. | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171543-A1 | MCL1 INHIBITORS | MCL1, BCL2L1, BCLAF1 | DNM1 521/4885EBP 780/4885SIGMAR1 3384/4885 |
| US-11667652-B2 | MCL1 inhibitors | MCL1, BCL2L1, BCLAF1 | DNM1 521/4885EBP 780/4885SIGMAR1 3384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.