Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 6/20 | 0.33 |
| ▸ | NOS2 | P35228 | 6/20 | 0.33 |
| ▸ | NOS3 | P29474 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23481987 | 0.77 | SMN1; SMN2 (0.38) | NOS1NOS2NOS3SMN1; SMN2ALDH1A1 | |
| SCHEMBL23482085 | 0.74 | USP2 (0.33) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL16199730 | 0.71 | LOXL2 (0.39) | LOXL2ENPP2ABATCSNK2A1 | |
| SCHEMBL17196021 | 0.71 | LOXL2 (0.39) | LOXL2ENPP2ABATCSNK2A1KDM4E | |
| SCHEMBL24362844 | 0.67 | PRKCI (0.34) | — | |
| SCHEMBL23482021 | 0.66 | SMN1; SMN2 (0.35) | NOS1NOS2NOS3SMN1; SMN2ALDH1A1 | |
| SCHEMBL27526860 | 0.66 | HSP90AB1 (0.44) | SMN1; SMN2ALDH1A1LOXL2KDM4EPSIP1 | |
| SCHEMBL13385346 | 0.65 | LOXL2 (0.50) | SMN1; SMN2ALDH1A1CYP3A4LOXL2ENPP2 | |
| SCHEMBL8211010 | 0.64 | ALDH1A1 (0.52) | NOS1NOS2NOS3SMN1; SMN2ALDH1A1 | |
| SCHEMBL14081605 | 0.64 | ENPP2 (0.52) | SMN1; SMN2ALDH1A1LOXL2ENPP2ABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021111124-A1 | POLYHETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS | STORM THERAPEUTICS LIMITED (GB) | 2021-06-10 | — | — | WO | disclosed |