Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31566099 | 0.82 | — | — | |
| SCHEMBL17196021 | 0.79 | LOXL2 (0.39) | LOXL2HRH3ROCK1ABATPNMT | |
| SCHEMBL9156124 | 0.78 | HRH3 (0.34) | LOXL2HRH3ABATPNMTENPP2 | |
| SCHEMBL20194342 | 0.75 | CSNK2A1 (0.41) | LOXL2HRH3PNMTGAAPKM | |
| SCHEMBL10608097 | 0.73 | XDH (0.38) | LOXL2HRH3ROCK1GAA | |
| SCHEMBL3680895 | 0.73 | CASP1 (0.42) | HRH3 | |
| SCHEMBL13385346 | 0.72 | LOXL2 (0.50) | LOXL2HRH3ROCK1ABATPNMT | |
| SCHEMBL4036805 | 0.71 | ALDH1A1 (0.46) | PKM | |
| SCHEMBL23482122 | 0.71 | NOS1 (0.33) | LOXL2ABATENPP2CSNK2A1 | |
| SCHEMBL16199733 | 0.71 | LOXL2 (0.46) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403852-B1 | 2-AMINOBENZIMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INT (DE) | 2014-10-29 | — | — | EP | disclosed |