Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13156892 | 0.76 | — | — | |
| SCHEMBL2776823 | 0.76 | TSHR (0.47) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL23482159 | 0.76 | LMNA (0.40) | — | |
| SCHEMBL10427084 | 0.73 | TSHR (0.38) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL19037374 | 0.72 | LMNA (0.54) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL6860577 | 0.70 | — | — | |
| SCHEMBL23482140 | 0.68 | PNMT (0.35) | PNMT | |
| SCHEMBL8917048 | 0.67 | MEN1 (0.46) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL13104453 | 0.67 | TSHR (0.42) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL147105 | 0.66 | PNMT (0.53) | MEN1TSHRCYP2C19RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113809-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | GENZYME CORPORATION (US) | 2021-06-10 | — | — | WO | disclosed |