Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10138023 | 0.91 | TSHR (0.37) | PBRM1KMT2AMEN1SLC16A3TSHR | |
| SCHEMBL4011696 | 0.89 | KMT2A (0.41) | KMT2AMEN1SIRT2HMGB1CYP3A4 | |
| SCHEMBL4363671 | 0.88 | DPP4 (0.37) | KMT2AMEN1HSP90B1HSP90AA1POLB | |
| SCHEMBL4356056 | 0.83 | L3MBTL1 (0.34) | KMT2AMEN1TSHRCYP1A2PKM | |
| SCHEMBL4361731 | 0.83 | L3MBTL1 (0.32) | KMT2AMEN1HSP90B1CYP1A2CYP2C9 | |
| SCHEMBL4358865 | 0.81 | ALDH1A1 (0.36) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL4011884 | 0.80 | ALDH1A1 (0.36) | KMT2AMEN1TSHRCYP1A2CYP2C19 | |
| SCHEMBL15624021 | 0.79 | SLC16A3 (0.34) | PBRM1SLC16A3TSHRSIRT2CCR9 | |
| SCHEMBL4422459 | 0.76 | L3MBTL1 (0.37) | KMT2AMEN1SLC16A3TSHRL3MBTL1 | |
| SCHEMBL4018520 | 0.75 | KMT2A (0.41) | KMT2AMEN1SIRT2HMGB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781675-B1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES INC (US) | 2014-03-26 | — | — | EP | disclosed |
| US-8389745-B2 | Phosphonate fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2013-03-05 | — | — | US | disclosed |
| US-20120116079-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | ELITECHGROUP MDX LLC | 2012-05-10 | — | — | US | disclosed |
| US-8008522-B2 | Phosphonate fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2011-08-30 | — | — | US | disclosed |
| US-20100261903-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | ELITECHGROUP MDX LLC | 2010-10-14 | — | — | US | disclosed |
| US-7767834-B2 | Phosphonylated fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2010-08-03 | — | — | US | disclosed |
| US-7671218-B2 | Phosphonate fluorescent dyes and conjugates | Elitech Holdings B.V. (NL) | 2010-03-02 | — | — | US | disclosed |
| EP-1991552-A2 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | Epoch Biosciences, Inc. (US) | 2008-11-19 | — | — | EP | disclosed |
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| WO-2007098182-A2 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2007-08-30 | — | — | WO | disclosed |
| US-20070172832-A1 | Phosphonate fluorescent dyes and conjugates | EPOCH BIOSCIENCES, INC. (US) | 2007-07-26 | — | — | US | disclosed |
| US-20060199955-A1 | Phosphonylated fluorescent dyes and conjugates | EPOCH BIOSCIENCES, INC. (US) | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261903-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | PHOSPHO1, PFAS, PHPT1 | PBRM1 3721/4885KMT2A 3091/4885MEN1 1647/4885 |
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | PHOSPHO1, PFAS, PHPT1 | PBRM1 3464/4885KMT2A 3036/4885MEN1 1539/4885 |
| US-20070172832-A1 | Phosphonate fluorescent dyes and conjugates | PHOSPHO1, PFAS, PHPT1 | PBRM1 3721/4885KMT2A 3091/4885MEN1 1647/4885 |
| US-20060199955-A1 | Phosphonylated fluorescent dyes and conjugates | PHOSPHO1, PFAS, PHPT1 | PBRM1 3464/4885KMT2A 3036/4885MEN1 1539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.