Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055948 | 0.85 | TDP1 (0.47) | TDP1GAAALDH1A1HSD11B1HSD17B3 | |
| SCHEMBL11644874 | 0.74 | CA2 (0.52) | TDP1POLBGAAALDH1A1MAPT | |
| SCHEMBL9495042 | 0.73 | TDP1 (0.67) | TDP1ALDH1A1MAPTCA12CA2 | |
| SCHEMBL8379811 | 0.73 | HSD11B1 (0.68) | TDP1GAAALDH1A1HSD11B1HSD17B3 | |
| SCHEMBL7336916 | 0.73 | ALDH1A1 (0.55) | TDP1POLBGAAGFERALDH1A1 | |
| SCHEMBL7336404 | 0.73 | TDP1 (0.60) | TDP1POLBGAAGFERALDH1A1 | |
| SCHEMBL5866138 | 0.73 | MEN1 (0.48) | TDP1ALDH1A1CYTH2MAPTALPL | |
| SCHEMBL28793114 | 0.72 | TDP1 (0.65) | TDP1ALDH1A1MAPTCA12CA2 | |
| SCHEMBL4622013 | 0.71 | TDP1 (0.64) | TDP1GAAALDH1A1MAPTALPL | |
| SCHEMBL23484449 | 0.71 | POLB (0.56) | TDP1POLBGAAGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171883-A1 | ANTIVIRAL WIPER | FUJIFILM CORPORATION (JP) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171883-A1 | ANTIVIRAL WIPER | CGAS, PRKX, PDE4C | TDP1 743/4885POLB 381/4885GAA 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.