SCHEMBL23484455

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL258619	0.89	HSP90AA1 (0.57)	HSP90AA1HSD17B10TSHRCA1CA2
	SCHEMBL11352238	0.86	HSP90AA1 (0.55)	HSP90AA1HSD17B10TSHRCA1CA2
	SCHEMBL8653830	0.85	TSHR (0.52)	HSP90AA1HSD17B10TSHRESR2CYP1A2
	SCHEMBL9445013	0.83	HSP90AA1 (0.68)	HSP90AA1HSD17B10TSHRCA1CA2
	SCHEMBL11045939	0.82	HSP90AA1 (0.60)	HSP90AA1HSD17B10TSHRCA1CA2
	SCHEMBL9623378	0.82	ESR1 (0.58)	HSP90AA1HSD17B10TSHRCA1CA2
	SCHEMBL9445002	0.81	HSP90AA1 (0.50)	HSP90AA1HSD17B10TSHRCA1CA2
	SCHEMBL7083294	0.80	LTA4H (0.54)	HSP90AA1HSD17B10TSHRCA1CA2
	SCHEMBL10704059	0.78	CA1 (0.61)	HSP90AA1HSD17B10TSHRCA1CA2
	SCHEMBL8652143	0.78	HSP90AA1 (0.47)	HSP90AA1HSD17B10TSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.