Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.31 |
| ▸ | WNT3A | P56704 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | PER2 | O15055 | 1/20 | 0.30 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.30 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL929430 | 0.82 | CYP2A6 (0.48) | DYRK1ACYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL219005 | 0.76 | — | — | |
| SCHEMBL20386530 | 0.74 | SLC6A2 (0.47) | DYRK1ACYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10051791 | 0.70 | CA2 (0.46) | DYRK1ACYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17010989 | 0.70 | CA2 (0.46) | DYRK1ACYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17740653 | 0.69 | CA2 (0.45) | DYRK1ACYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20408052 | 0.69 | SLC6A2 (0.40) | DYRK1ACYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL931734 | 0.68 | ALDH1A1 (0.48) | DYRK1A | |
| SCHEMBL10369395 | 0.68 | CYP2A6 (0.46) | DYRK1ACYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17010919 | 0.68 | CYP2A6 (0.46) | DYRK1ACYP2A6SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361444-A1 | MATERIALS | Lomox Limited (GB) | 2011-08-31 | — | — | EP | disclosed |
| WO-2009103952-A1 | MATERIALS | LOMOX LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |