SCHEMBL23485706

SCHEMBL23485706

COc1ccc(O[C@H](O)C2CCC(C(=O)O)CC2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.51
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
VCP P55072 1/20 0.44
HPGD P15428 1/20 0.43
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
TAS1R2 Q8TE23 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
TAS2R14 Q9NYV8 1/20 0.40
NEK2 P51955 1/20 0.39
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18879707 0.76 KMT2A (0.59) GAANPC1RAB9AHPGDCES2
SCHEMBL19431510 0.76 KMT2A (0.59) GAANPC1RAB9AHPGDCES2
SCHEMBL2723977 0.76 NPC1 (0.60) GAANPC1RAB9AHPGDCES2
SCHEMBL21908582 0.73 HTT (0.51) HPGDKMT2A
SCHEMBL23720974 0.73 HTT (0.51) HPGDKMT2A
SCHEMBL8861184 0.73 GAA (0.43) GAANPC1RAB9AVCPKMT2A
SCHEMBL11457462 0.72 TAS2R14 (0.53) GAAVCPKMT2ATAS2R14
SCHEMBL19431496 0.71 GAA (0.57) GAANPC1RAB9ACES2CES1
SCHEMBL23185889 0.70 THRB (0.51) KMT2AKDM4E
SCHEMBL2074046 0.70 GAA (0.64) GAAKMT2ANEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030859-B2 Polymerizable compound, polymerizable composition and optical film DONGJIN SEMICHEM CO., LTD. (KR) 2024-07-09 US disclosed
US-20210171478-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION AND OPTICAL FILM DONGJIN SEMICHEM CO., LTD. (KR) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210171478-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION AND OPTICAL FILM PARG, PUF60, CRY2 GAA 3401/4885NPC1 2335/4885RAB9A 2159/4885
US-12030859-B2 Polymerizable compound, polymerizable composition and optical film PARG, PUF60, CRY2 GAA 3401/4885NPC1 2335/4885RAB9A 2159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.