Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 2/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 2/20 | 0.47 |
| ▸ | EDNRB | P24530 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31154321 | 0.90 | AKR1C3 (0.65) | NPC1RAB9AGAAPDE4APDE4B | |
| SCHEMBL31154367 | 0.90 | AKR1C3 (0.65) | NPC1RAB9AGAAPDE4APDE4B | |
| Bicarbonate SCHEMBL6207408 | 0.89 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19737310 | 0.86 | PDE4A (0.55) | NPC1RAB9AGAAPDE4APDE4B | |
| SCHEMBL2724290 | 0.85 | PKM (0.54) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2724289 | 0.85 | PKM (0.54) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16708937 | 0.84 | NAAA (0.51) | NPC1RAB9AGAAPDE4APDE4B | |
| SCHEMBL2725346 | 0.84 | NAAA (0.51) | NPC1RAB9AGAAPDE4APDE4B | |
| SCHEMBL16699888 | 0.84 | NAAA (0.51) | NPC1RAB9AGAAPDE4APDE4B | |
| SCHEMBL19513631 | 0.84 | NPC1 (0.54) | NPC1RAB9AGAAPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1075445-A | — | — | None | — | — | JP | disclosed |
| US-11193065-B2 | Liquid crystal composition, method of producing the same, and retardation film constituted from the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-12-07 | — | — | US | disclosed |
| US-10858590-B2 | Compound, liquid crystal composition, optical film, polarizing plate, and optical display | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-12-08 | — | — | US | disclosed |
| US-20200165519-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND RETARDATION PLATE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-05-28 | — | — | US | disclosed |
| US-10336938-B2 | Liquid crystal composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-07-02 | — | — | US | disclosed |
| US-20180120624-A1 | COMPOUND, LIQUID CRYSTAL COMPOSITION, OPTICAL FILM, POLARIZING PLATE, AND OPTICAL DISPLAY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-03 | — | — | US | disclosed |
| US-20180119015-A1 | COMPOUND, LIQUID CRYSTAL COMPOSITION, OPTICAL FILM, POLARIZING PLATE, AND OPTICAL DISPLAY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-03 | — | — | US | disclosed |
| US-20170335191-A1 | LIQUID CRYSTAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-11-23 | — | — | US | disclosed |
| US-20170306234-A1 | LIQUID CRYSTAL COMPOSITION, METHOD OF PRODUCING THE SAME, AND RETARDATION FILM CONSTITUTED FROM THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-26 | — | — | US | disclosed |
| US-20170283700-A1 | LIQUID CRYSTAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-05 | — | — | US | disclosed |
| EP-2632269-A1 | CYCLIC AMINE SUBSTITUTED OXAZOLIDINONE CETP INHIBITOR | Merck Sharp & Dohme Corp. (US) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012058187-A1 | CYCLIC AMINE SUBSTITUTED OXAZOLIDINONE CETP INHIBITOR | MERCK SHARP & DOHME CORP. (US) | 2012-05-03 | — | — | WO | disclosed |
| EP-0681569-B1 | SPIROCYCLOALKYL-SUBSTITUTED AZETIDINONES USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | SCHERING CORP (US) | 2001-03-21 | — | — | EP | disclosed |
| US-5698548-A | Spirocycloalkyl-substituted azetidinones useful as hypocholesterolemic agents | SCHERING CORPORATION (US) | 1997-12-16 | — | — | US | disclosed |
| EP-0681569-A1 | SPIROCYCLOALKYL-SUBSTITUTED AZETIDINONES USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | SCHERING CORPORATION (US) | 1995-11-15 | — | — | EP | disclosed |
| WO-1994017038-A1 | SPIROCYCLOALKYL-SUBSTITUTED AZETIDINONES USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | SCHERING CORPORATION (US) | 1994-08-04 | — | — | WO | disclosed |
| JP-S6475445-A | PRODUCTION OF 4'-HYDROXYBIPHENYL-4-CARBOXYLIC ACID | MITSUI TOATSU CHEMICALS | 1989-03-22 | — | — | JP | disclosed |
| US-4029595-A | Novel liquid crystal compounds and electro-optic devices incorporating them | RCA CORPORATION (US) | 1977-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180119015-A1 | COMPOUND, LIQUID CRYSTAL COMPOSITION, OPTICAL FILM, POLARIZING PLATE, AND OPTICAL DISPLAY | RCC1, MITF, FZD7 | NPC1 1380/4885RAB9A 609/4885GAA 3972/4885 |
| US-20170335191-A1 | LIQUID CRYSTAL COMPOSITION | RCC1, CCDC47, ACIN1 | NPC1 2687/4885RAB9A 1008/4885GAA 3239/4885 |
| US-10858590-B2 | Compound, liquid crystal composition, optical film, polarizing plate, and optical display | RCC1, MITF, FZD7 | NPC1 1380/4885RAB9A 609/4885GAA 3972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.