Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 2/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486582 | 0.80 | DHODH (0.38) | VCPMAPKAPK2DHODHGSK3BMMP3 | |
| SCHEMBL23453725 | 0.74 | KDM4E (0.43) | DHODHGSK3B | |
| SCHEMBL23453756 | 0.74 | CSF1R (0.40) | VCPMAPKAPK2DHODHGSK3BCYP2C9 | |
| SCHEMBL22609261 | 0.70 | KDM4E (0.46) | DHODHGSK3BMEN1KMT2A | |
| SCHEMBL22609280 | 0.69 | GSK3A (0.42) | VCPDHODHGSK3BCSF1RGAA | |
| SCHEMBL23453734 | 0.67 | SYK (0.43) | CSF1RABCG2ABCB1ABCC1 | |
| SCHEMBL25546850 | 0.64 | MMP3 (0.56) | VCPMAPKAPK2DHODHGSK3BMMP3 | |
| SCHEMBL22609264 | 0.60 | RXFP1 (0.43) | DHODHGSK3BCYP2C9CYP2C19MEN1 | |
| SCHEMBL21915358 | 0.60 | CTSK (0.54) | VCPDHODHGSK3BMMP3CYP2C9 | |
| SCHEMBL23453717 | 0.60 | DHODH (0.41) | MAPKAPK2DHODHGSK3BCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | ORFAN BIOTECH SL (ES) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | PNPO, XDH, GLS | VCP 3734/4885MAPKAPK2 1986/4885DHODH 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.