SCHEMBL2348686

SCHEMBL2348686

CC(=O)CCCCCCCCCCCCC(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.71
LMNA P02545 3/20 0.71
NFKB1 P19838 1/20 0.71
PMP22 Q01453 1/20 0.71
SLC15A2 Q16348 1/20 0.63
GPR84 Q9NQS5 8/20 0.62
PPARG P37231 7/20 0.62
PPARD Q03181 7/20 0.62
PPARA Q07869 7/20 0.62
HDAC11 Q96DB2 5/20 0.62
PTPN1 P18031 3/20 0.62
ALDH1A1 P00352 2/20 0.62
TLR2 O60603 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
FABP4 P15090 2/20 0.62
FFAR1 O14842 2/20 0.62
FFAR4 Q5NUL3 2/20 0.62
SLC22A6 Q4U2R8 1/20 0.62
SLC22A8 Q8TCC7 1/20 0.62
MEN1 O00255 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL561614 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL2350916 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL2346452 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL2348213 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL2989964 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL24538421 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL2350035 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL15903953 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL230198 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL2346285 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025003023-A1 METHOD FOR PRODUCING A CARBOXYLIC ACID EVONIK OPERATIONS GMBH (DE) 2025-01-02 WO disclosed
US-20230203100-A1 COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE PEP2TANGO THERAPEUTICS INC. 2023-06-29 US disclosed
US-11352406-B2 Insulin derivatives and the medical uses hereof NOVO NORDISK A/S (DK) 2022-06-07 US disclosed
US-20200283493-A1 Novel Insulin Derivatives and the Medical Uses Hereof NOVO NORDISK AS (DK) 2020-09-10 US disclosed
US-10040839-B2 Insulin derivatives and the medical uses hereof NOVO NORDISK A/S (DK) 2018-08-07 US disclosed
US-10040839-B2 Insulin derivatives and the medical uses hereof NOVO NORDISK A/S (DK) 2018-08-07 US disclosed
WO-2017197048-A1 ALBUMIN BINDING CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME AMUNIX OPERATING INC. (US) 2017-11-16 WO disclosed
US-20170145069-A1 GLP-1 Derivatives NOVO NORDISK AS (DK) 2017-05-25 US disclosed
US-20170145059-A1 Novel Amylin And Calcitonin Receptor Agonist NOVO NORDISK AS (DK) 2017-05-25 US disclosed
US-20170145059-A1 Novel Amylin And Calcitonin Receptor Agonist NOVO NORDISK AS (DK) 2017-05-25 US disclosed
US-20150368313-A1 Novel Glucagon Analogues NOVO NORDISK AS (DK) 2015-12-24 US disclosed
US-20150210745-A1 Double-Acylated GLP-1 Derivatives with a Linker NOVO NORDISK AS (DK) 2015-07-30 US disclosed
US-20140303083-A1 GLP-1 Derivatives NOVO NORDISK A/S (DK) 2014-10-09 US disclosed
US-20130288960-A1 Double-Acylated GLP-1 Derivatives NOVO NORDISK A/S (DK) 2013-10-31 US disclosed
EP-1544190-B1 METHOD FOR PRODUCING CARBOXYLIC ACIDS NAT INST OF ADVANCED IND SCIEN (JP) 2011-08-31 EP disclosed
CN-1313428-C Method for producing carboxylic acid NAT INST OF ADVANCED IND SCIEN (JP) 2007-05-02 CN disclosed
US-7186858-B2 Method for producing carboxylic acid NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2007-03-06 US disclosed
US-20050215817-A1 Method for producing carboxylic acid NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2005-09-29 US disclosed
CN-1671642-A Process for producing carboxylic acid NAT INST OF ADV IND & TECHNOL (JP) 2005-09-21 CN disclosed
EP-1544190-A1 METHOD FOR PRODUCING CARBOXYLIC ACID National Institute of Advanced Industrial Science and Technology (JP) 2005-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150210745-A1 Double-Acylated GLP-1 Derivatives with a Linker GLP1R, VIP, IAPP TSHR 1003/4885LMNA 1390/4885NFKB1 2452/4885
US-11352406-B2 Insulin derivatives and the medical uses hereof IAPP, INSR, IRS1 TSHR 843/4885LMNA 2035/4885NFKB1 2448/4885
US-20170145069-A1 GLP-1 Derivatives GLP1R, GIPR, GCG TSHR 447/4885LMNA 1914/4885NFKB1 2538/4885
US-20230203100-A1 COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE IAPP, GPR119, GIPR TSHR 443/4885LMNA 2355/4885NFKB1 3464/4885
US-20170145059-A1 Novel Amylin And Calcitonin Receptor Agonist SCTR, CALCRL, IAPP TSHR 255/4885LMNA 2777/4885NFKB1 2694/4885
US-20050215817-A1 Method for producing carboxylic acid ADH1C, HAO2, ALDH2 TSHR 2104/4885LMNA 3596/4885NFKB1 1961/4885
US-20140303083-A1 GLP-1 Derivatives GLP1R, GIPR, GCG TSHR 430/4885LMNA 1266/4885NFKB1 1831/4885
US-10040839-B2 Insulin derivatives and the medical uses hereof IAPP, INSR, IRS1 TSHR 843/4885LMNA 2035/4885NFKB1 2448/4885
US-20150368313-A1 Novel Glucagon Analogues GLP1R, GCG, IAPP TSHR 394/4885LMNA 2544/4885NFKB1 3262/4885
US-20130288960-A1 Double-Acylated GLP-1 Derivatives GLP1R, VIP, IAPP TSHR 1103/4885LMNA 2011/4885NFKB1 2793/4885
US-20200283493-A1 Novel Insulin Derivatives and the Medical Uses Hereof IAPP, INSR, GPR119 TSHR 1024/4885LMNA 2407/4885NFKB1 2577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.