Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ASPH | Q12797 | 3/20 | 0.44 |
| ▸ | KDM8 | Q8N371 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMO | O15229 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5818329 | 0.79 | KDM4E (0.47) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL439545 | 0.79 | KDM4E (0.47) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL2339609 | 0.78 | L3MBTL1 (0.45) | KDM4EALDH1A1ALOX15NPSR1L3MBTL1 | |
| SCHEMBL29683329 | 0.78 | KDM4E (0.46) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL6903612 | 0.78 | KDM4E (0.50) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL2238874 | 0.78 | DPP4 (0.47) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL2878004 | 0.78 | KDM4E (0.60) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL31500594 | 0.78 | DPP4 (0.47) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL30991615 | 0.78 | KDM4E (0.46) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL28177119 | 0.76 | KDM4E (0.53) | KDM4EASPHKDM8ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926788-B | Substituted piperidine analog derivative, the pharmaceutical composition containing it and its application in antitumor | 浙江大学 | 2018-08-28 | — | — | CN | disclosed |
| EP-1498413-B1 | 4-Aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2011-08-31 | — | — | EP | disclosed |
| EP-2187893-A2 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | Anacor Pharmaceuticals, Inc. (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009111676-A2 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2009-09-11 | — | — | WO | disclosed |
| EP-1246802-B1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2007-03-14 | — | — | EP | disclosed |
| CN-1281591-C | 4-aminopyridinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2006-10-25 | — | — | CN | disclosed |
| EP-1498413-A1 | 4-Aminopicolinates and their use as herbicides | Dow AgroSciences LLC (US) | 2005-01-19 | — | — | EP | disclosed |
| CN-1416419-A | 4-aminopyridinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2003-05-07 | — | — | CN | disclosed |
| EP-1246802-A1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2002-10-09 | — | — | EP | disclosed |
| US-20010047099-A1 | 4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC | 2001-11-29 | — | — | US | disclosed |
| US-6297197-B1 | DEMONSTRATING A BROAD SPECTRUM OF WEED CONTROL. | DOW AGROSCIENCES LLC | 2001-10-02 | — | — | US | disclosed |
| WO-2001051468-A1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010047099-A1 | 4-aminopicolinates and their use as herbicides | AADAT, ABAT, DDT | KDM4E 668/4885ASPH 245/4885KDM8 3355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.