SCHEMBL439545

SCHEMBL439545

O=C(O)c1nccc(Cl)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.47
ASPH Q12797 3/20 0.47
KDM8 Q8N371 3/20 0.47
MAPT P10636 3/20 0.45
TSHR P16473 2/20 0.45
ALDH1A1 P00352 2/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX15 P16050 1/20 0.45
BLM P54132 1/20 0.45
AGER Q15109 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KMO O15229 6/20 0.42
CYP1A2 P05177 1/20 0.40
KDM5A P29375 2/20 0.40
KDM4C Q9H3R0 2/20 0.40
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30991615 0.98 KDM4E (0.46) KDM4EASPHKDM8MAPTTSHR
SCHEMBL29683329 0.98 KDM4E (0.46) KDM4EASPHKDM8MAPTTSHR
Pyridine SCHEMBL29163904 0.91 KDM4E (0.43) KDM4EASPHKDM8MAPTTSHR
Alcohol SCHEMBL29172362 0.89 KDM4E (0.40) KDM4EASPHKDM8MAPTTSHR
Alcohol SCHEMBL28198756 0.89 KDM4E (0.40) KDM4EASPHKDM8MAPTTSHR
Ethylamine SCHEMBL28386133 0.89 KDM4E (0.40) KDM4EASPHKDM8MAPTTSHR
Isopropyl Alcohol SCHEMBL29172361 0.89 KDM4E (0.40) KDM4EASPHKDM8MAPTTSHR
Isopropyl Alcohol SCHEMBL29039886 0.89 KDM4E (0.40) KDM4EASPHKDM8MAPTTSHR
SCHEMBL28345283 0.88 KDM4E (0.39) KDM4EASPHKDM8MAPTTSHR
Monoethanolamine SCHEMBL28205512 0.88 KDM4E (0.39) KDM4EASPHKDM8MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 515 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240172753-A1 AGRICULTURAL FORMULATIONS STEPAN COMPANY 2024-05-30 US claimed
EP-4312553-A1 AGRICULTURAL FORMULATIONS Stepan Company (US) 2024-02-07 EP claimed
WO-2022212185-A1 AGRICULTURAL FORMULATIONS STEPAN COMPANY (US) 2022-10-06 WO claimed
US-20130316907-A1 PROCESS FOR PREPARATION OF HERBICIDAL SALTS NUFARM AUSTRALIA LIMITED (AU) 2013-11-28 US claimed
WO-2011143690-A1 PROCESS FOR PREPARATION OF HERBICIDAL SALTS NUFARM AUSTRALIA LIMITED (AU) 2011-11-24 WO claimed
WO-2003094614-A1 AUXILIARY COMPOSITIONS BIOTECH SCIENCE PTY LTD (AU) 2003-11-20 WO claimed
EP-0254982-A2 Electrolytic cell with nickel alloy anodes for electrochemical dechlorination DOWELANCO (US) 1988-02-03 EP claimed
US-12595273-B2 Phosphonate conjugates and uses thereof TRANSLATIONAL GENOMICS RES INST (US) 2026-04-07 US disclosed
US-20260085032-A1 NOVEL SURFACTANTS DERIVED FROM GLYCIDYL ESTERS OF ROSIN ACIDS LAMBERTI SPA (IT) 2026-03-26 US disclosed
US-12448391-B2 Bicyclic derivatives for treating endoparasites ELANCO TIERGESUNDHEIT AG (CH) 2025-10-21 US disclosed
EP-4572608-A1 NOVEL SURFACTANTS DERIVED FROM GLYCIDYL ESTERS OF ROSIN ACIDS Lamberti SPA (IT) 2025-06-25 EP disclosed
CN-111356684-B Herbicidal pyridyl ethers 巴斯夫欧洲公司 2025-03-28 CN disclosed
CN-119584862-A Herbicide suspension concentrate and preparation method thereof 澳大利亚纽法姆有限公司 2025-03-07 CN disclosed
EP-0257822-A2 Substituted triazolyl-2-butanol derivatives as plant growth regulating agents IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-03-02 EP disclosed
EP-0254982-A2 Electrolytic cell with nickel alloy anodes for electrochemical dechlorination DOWELANCO (US) 1988-02-03 EP disclosed
EP-0252520-A1 Process for silver cathode activation DOWELANCO (US) 1988-01-13 EP disclosed
CN-86100814-A A type-A heavy smog preparation without pollution 1987-08-26 CN disclosed
US-4616087-A ANTIVIRAL ACTIVITY THE DOW CHEMICAL COMPANY (US) 1986-10-07 US disclosed
US-4371537-A Sulfur-substituted phenoxypyridines having antiviral activity THE DOW CHEMICAL COMPANY (US) 1983-02-01 US disclosed
US-4217185-A Electrolytic production of certain trichloropicolinic acids and/or 3,6-dichloropicolinic acid THE DOW CHEMICAL COMPANY (US) 1980-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085032-A1 NOVEL SURFACTANTS DERIVED FROM GLYCIDYL ESTERS OF ROSIN ACIDS PHOSPHO1, CERT1, SGMS1 KDM4E 4101/4885ASPH 2681/4885KDM8 3470/4885
US-12448391-B2 Bicyclic derivatives for treating endoparasites TBXA2R, PIGS, CYCS KDM4E 2087/4885ASPH 3825/4885KDM8 2337/4885
US-20240172753-A1 AGRICULTURAL FORMULATIONS PNPO, IP6K3, PHOSPHO1 KDM4E 2489/4885ASPH 543/4885KDM8 2698/4885
US-20130316907-A1 PROCESS FOR PREPARATION OF HERBICIDAL SALTS DDT, DDC, HDHD5 KDM4E 260/4885ASPH 28/4885KDM8 470/4885
US-12595273-B2 Phosphonate conjugates and uses thereof RET, PTK2, ERBB2 KDM4E 3638/4885ASPH 4424/4885KDM8 3330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.