SCHEMBL2348827

SCHEMBL2348827

CC(C)(C)c1ccc(N(c2ccc(C3=CCC(c4ccccc4)(N(c4ccc(C(C)(C)C)cc4)c4ccc(C(C)(C)C)cc4)C=C3)cc2)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2343295 0.90 HSD11B1 (0.32)
SCHEMBL4213712 0.89 KDM4E (0.32)
SCHEMBL4849975 0.88 KDM4E (0.31)
SCHEMBL8862832 0.81 ICMT (0.30)
SCHEMBL2348248 0.81 HSD11B1 (0.36)
SCHEMBL26088275 0.80
SCHEMBL2328838 0.79
SCHEMBL222468 0.79 TP53 (0.31)
SCHEMBL3734729 0.79 HTR7 (0.31)
SCHEMBL223518 0.78 CNR2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7642029-B2 Imaging member XEROX CORPORATION (US) 2010-01-05 US claimed
US-7527903-B2 Imaging member XEROX CORPORATION (US) 2009-05-05 US claimed
US-20070172749-A1 Imaging member XEROX CORPORATION 2007-07-26 US claimed
US-8877413-B2 Flexible imaging members comprising improved ground strip XEROX CORPORATION (US) 2014-11-04 US disclosed
US-20130052576-A1 FLEXIBLE IMAGING MEMBERS COMPRISING IMPROVED GROUND STRIP XEROX CORPORATION (US) 2013-02-28 US disclosed
US-8343700-B2 Imaging members having stress/strain free layers XEROX CORPORATION (US) 2013-01-01 US disclosed
US-8232030-B2 Curl-free imaging members with a slippery surface XEROX CORPORATION (US) 2012-07-31 US disclosed
US-20110256474-A1 IMAGING MEMBERS HAVING STRESS/STRAIN FREE LAYERS XEROX CORPORATION (US) 2011-10-20 US disclosed
US-20110229808-A1 CURL-FREE IMAGING MEMBERS WITH A SLIPPERY SURFACE XEROX CORPORATION (US) 2011-09-22 US disclosed
US-20110207038-A1 SLIPPERY SURFACE IMAGING MEMBERS XEROX CORPORATION (US) 2011-08-25 US disclosed
US-7829252-B2 Imaging member XEROX CORPORATION (US) 2010-11-09 US disclosed
US-7611811-B2 Imaging member XEROX CORPORATION (US) 2009-11-03 US disclosed
US-7538175-B2 Phenolic hole transport polymers XEROX CORPORATION (US) 2009-05-26 US disclosed
US-7413835-B2 Imaging members XEROX CORPORATION (US) 2008-08-19 US disclosed
US-20070148572-A1 Imaging member XEROX CORPORATION 2007-06-28 US disclosed
US-20070099101-A1 Imaging member XEROX CORPORATION 2007-05-03 US disclosed
US-20070087276-A1 Phenolic hole transport polymers XEROX CORPORATON. 2007-04-19 US disclosed
EP-1775637-A1 Phenolic hole transport polymers Xerox Corporation (US) 2007-04-18 EP disclosed
US-20070054208-A1 Imaging member XEROX CORPORATION 2007-03-08 US disclosed
US-20070015073-A1 charge transport layers comprising charge transport compounds, thermoplastic binder resins, particle dispersions and polycarbonates, exhibits enhanced wear resistance, excellent photoelectrical properties and good print quality; electrography XEROX CORPORATION 2007-01-18 US disclosed