Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 5/20 | 0.62 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.62 |
| ▸ | JAK2 | O60674 | 2/20 | 0.57 |
| ▸ | TYK2 | P29597 | 2/20 | 0.57 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23488122 | 0.88 | KCNK3 (0.66) | KCNK3KCNK9JAK2TYK2GRM4 | |
| SCHEMBL14876237 | 0.85 | KCNK3 (0.62) | KCNK3KCNK9JAK2TYK2GRM4 | |
| SCHEMBL31580980 | 0.82 | NPC1 (0.59) | KCNK3KCNK9JAK2TYK2GRM4 | |
| SCHEMBL14875919 | 0.82 | RAB9A (0.62) | KCNK3KCNK9JAK2TYK2GRM4 | |
| SCHEMBL28292635 | 0.82 | SCN10A (0.44) | KCNK3KCNK9MAPT | |
| SCHEMBL1268265 | 0.81 | JAK2 (0.62) | KCNK3KCNK9JAK2TYK2PABPC1 | |
| SCHEMBL31633789 | 0.80 | ACVRL1 (0.52) | MEN1MAPTKMT2AHPGD | |
| SCHEMBL31580868 | 0.78 | KCNK3 (0.58) | KCNK3KCNK9GRM4PABPC1NPC1 | |
| SCHEMBL5007785 | 0.78 | EGFR (0.41) | KCNK3KCNK9NPC1RAB9ASIRT1 | |
| SCHEMBL28821933 | 0.78 | JAK2 (0.63) | KCNK3KCNK9JAK2TYK2GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | KCNK3 4073/4885KCNK9 4061/4885JAK2 4701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.