SCHEMBL23488490

SCHEMBL23488490

CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1OC(=O)c1cccc(OCc2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 5/20 0.53
LGALS8 O00214 4/20 0.53
LGALS9 O00182 4/20 0.53
LGALS1 P09382 4/20 0.53
LGALS7; LGALS7B P47929 4/20 0.53
MAOB P27338 1/20 0.48
ALDH1A1 P00352 1/20 0.48
NR4A2 P43354 1/20 0.47
PTPN1 P18031 3/20 0.45
LGALS4 P56470 1/20 0.45
OGA O60502 1/20 0.44
SMPD1 P17405 1/20 0.44
HIF1A Q16665 1/20 0.44
SLC5A1 P13866 1/20 0.44
SLC5A2 P31639 1/20 0.44
MRGPRX4 Q96LA9 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23488417 0.89 LGALS8 (0.53) LGALS3LGALS8LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488143 0.89 LGALS8 (0.53) LGALS3LGALS8LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488412 0.89 LGALS8 (0.53) LGALS3LGALS8LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488429 0.88 LGALS8 (0.48) LGALS3LGALS8LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488618 0.88 LGALS8 (0.48) LGALS3LGALS8LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488483 0.85 LGALS3 (0.49) LGALS3LGALS8LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488492 0.85 LGALS3 (0.49) LGALS3LGALS8LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488494 0.85 NPC1 (0.50) LGALS3LGALS8LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL11371729 0.84 LGALS3 (0.60) LGALS3LGALS8LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL11368063 0.84 LGALS3 (0.60) LGALS3LGALS8LGALS9LGALS1LGALS7; LGALS7B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 LGALS3 156/4885LGALS8 61/4885LGALS9 106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.