SCHEMBL23488143

SCHEMBL23488143

CO[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1OC(=O)c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 4/20 0.53
LGALS3 P17931 7/20 0.51
LGALS4 P56470 3/20 0.51
LGALS9 O00182 4/20 0.48
LGALS1 P09382 4/20 0.48
LGALS7; LGALS7B P47929 3/20 0.48
OGA O60502 1/20 0.46
MAOB P27338 2/20 0.46
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
SELP P16109 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23488412 1.00 LGALS8 (0.53) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL23488417 1.00 LGALS8 (0.53) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL23488419 0.92 LGALS8 (0.49) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL23488513 0.92 LGALS8 (0.64) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL23488490 0.89 LGALS3 (0.53) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL23488416 0.88 LGALS9 (0.49) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488483 0.88 LGALS3 (0.49) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL11371729 0.87 LGALS3 (0.60) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL11368063 0.87 LGALS3 (0.60) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL23488618 0.87 LGALS8 (0.48) LGALS8LGALS3LGALS4LGALS9LGALS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 LGALS8 61/4885LGALS3 156/4885LGALS4 68/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.