SCHEMBL23488653

SCHEMBL23488653

CO[C@H]1O[C@H](CNC(=O)c2cc(Cl)c(OCc3ccccc3)c(Cl)c2)[C@@H](O)[C@H](O)[C@H]1NC(C)=O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.42
CA2 P00918 4/20 0.42
CA9 Q16790 4/20 0.42
LGALS3 P17931 3/20 0.42
LGALS9 O00182 1/20 0.42
LGALS7; LGALS7B P47929 1/20 0.42
MMP9 P14780 1/20 0.41
MMP12 P39900 1/20 0.41
HRAS P01112 1/20 0.41
POLB P06746 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23488754 0.94 SLC6A5 (0.42) CA1CA2CA9LGALS3LGALS9
SCHEMBL23488180 0.90 LGALS3 (0.44) CA1CA2CA9LGALS3LGALS9
SCHEMBL23488501 0.89 CA1 (0.52) CA1CA2CA9
SCHEMBL23488318 0.88 LGALS3 (0.41) LGALS3LGALS9LGALS7; LGALS7BMMP9MMP12
SCHEMBL23488313 0.88 LGALS3 (0.43) CA1CA2CA9LGALS3LGALS9
SCHEMBL23488739 0.88 LGALS3 (0.41) CA1CA2CA9LGALS3LGALS9
SCHEMBL23488481 0.86 KMT2A (0.39) CA1CA2CA9LGALS3LGALS9
SCHEMBL23488332 0.86 CA2 (0.54) CA1CA2CA9LGALS3LGALS7; LGALS7B
SCHEMBL23488670 0.86 CA2 (0.54) CA1CA2CA9LGALS3LGALS7; LGALS7B
SCHEMBL23488667 0.82 KDM4E (0.43) CA1CA2CA9MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 CA1 2052/4885CA2 1099/4885CA9 906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.