Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 4/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23452429 | 0.75 | ACHE (0.40) | MAPT | |
| SCHEMBL23492969 | 0.72 | MASP2 (0.49) | L3MBTL1SMN1; SMN2HTTROCK2GPR139 | |
| SCHEMBL23491352 | 0.70 | NPC1 (0.48) | L3MBTL1HPGDHTTGPR139TP53 | |
| SCHEMBL23478372 | 0.69 | NAMPT (0.43) | L3MBTL1LMNA | |
| SCHEMBL23491362 | 0.66 | F2 (0.44) | MAPK1POLBPRSS1PRSS2PRSS3 | |
| SCHEMBL16128275 | 0.63 | TAAR1 (0.53) | HPGDHTT | |
| SCHEMBL23493002 | 0.62 | BCHE (0.47) | L3MBTL1MAPTMAPK1 | |
| Trifluoroacetic Acid SCHEMBL23452232 | 0.62 | HTR6 (0.42) | MAPT | |
| SCHEMBL25054045 | 0.62 | NPC1 (0.47) | L3MBTL1MAPTHPGDHTTGPR139 | |
| SCHEMBL23478373 | 0.61 | HTR6 (0.51) | MAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113682-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2021-06-10 | — | — | WO | disclosed |