Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.75 |
| ▸ | P2RY2 | P41231 | 15/20 | 0.68 |
| ▸ | P2RY4 | P51582 | 10/20 | 0.68 |
| ▸ | P2RY6 | Q15077 | 8/20 | 0.68 |
| ▸ | POLA1 | P09884 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20798009 | 1.00 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| SCHEMBL27554036 | 1.00 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| SCHEMBL20074354 | 1.00 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| SCHEMBL12729520 | 1.00 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| SCHEMBL48209 | 1.00 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| SCHEMBL16633413 | 1.00 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| SCHEMBL8003 | 1.00 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| Water SCHEMBL3961110 | 0.99 | DUT (0.74) | DUTP2RY2P2RY4P2RY6POLA1 | |
| Bromide SCHEMBL18112592 | 0.99 | DUT (0.74) | DUTP2RY2P2RY4P2RY6POLA1 | |
| Iodide SCHEMBL7941539 | 0.99 | DUT (0.74) | DUTP2RY2P2RY4P2RY6POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008274-B2 | P1-(2′-deoxycytidine 5′-)P4-(uridine 5′-)tetraphosphate, tetra-(alkali metal) salt, for treating sinusitis | INSPIRE PHARMACEUTICALS, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| EP-1450820-A4 | METHOD FOR TREATING OR PREVENTING INFLAMMATORY DISEASES | INSPIRE PHARMACEUTICALS INC (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-1450820-A2 | METHOD FOR TREATING OR PREVENTING INFLAMMATORY DISEASES | Inspire Pharmaceuticals, Inc. (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003039473-A2 | METHOD FOR TREATING OR PREVENTING INFLAMMATORY DISEASES | INSPIRE PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | disclosed |