SCHEMBL48209

SCHEMBL48209

O=c1ccn([C@@H]2CC(O)[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1

nearest known ligand 0.75

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.75
P2RY2 P41231 15/20 0.68
P2RY4 P51582 10/20 0.68
P2RY6 Q15077 8/20 0.68
POLA1 P09884 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2349191 1.00 DUT (0.75) DUTP2RY2P2RY4P2RY6POLA1
SCHEMBL20798009 1.00 DUT (0.75) DUTP2RY2P2RY4P2RY6POLA1
SCHEMBL27554036 1.00 DUT (0.75) DUTP2RY2P2RY4P2RY6POLA1
SCHEMBL20074354 1.00 DUT (0.75) DUTP2RY2P2RY4P2RY6POLA1
SCHEMBL12729520 1.00 DUT (0.75) DUTP2RY2P2RY4P2RY6POLA1
SCHEMBL16633413 1.00 DUT (0.75) DUTP2RY2P2RY4P2RY6POLA1
SCHEMBL8003 1.00 DUT (0.75) DUTP2RY2P2RY4P2RY6POLA1
Water SCHEMBL3961110 0.99 DUT (0.74) DUTP2RY2P2RY4P2RY6POLA1
Bromide SCHEMBL18112592 0.99 DUT (0.74) DUTP2RY2P2RY4P2RY6POLA1
Iodide SCHEMBL7941539 0.99 DUT (0.74) DUTP2RY2P2RY4P2RY6POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 569 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9157073-B1 DNA polymerases NEW ENGLAND BIOLABS, INC. (US) 2015-10-13 US claimed
US-9127258-B2 DNA polymerases NEW ENGLAND BIOLABS, INC. (US) 2015-09-08 US claimed
EP-2170924-B1 5-BROMO-2'-DEOXY-URIDINE LABELED NUCLEOTIDE TRIPHOSPHATES AND NUCLEIC ACID PROBES AND METHODS OF MAKING AND USING THE SAME LIFE TECHNOLOGIES CORP (US) 2015-07-22 EP claimed
US-20150152396-A1 Novel DNA Polymerases BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2015-06-04 US claimed
US-8993298-B1 DNA polymerases NEW ENGLAND BIOLABS, INC. (US) 2015-03-31 US claimed
EP-2028272-B1 METHOD OF MODIFYING NUCLEOTIDE CHAIN PANASONIC CORP (JP) 2014-01-08 EP claimed
US-20120252030-A1 5-BROMO-2'-DEOXY-URIDINE LABELED NUCLEOTIDE TRIPHOSPHATES AND NUCLEIC ACID PROBES AND METHODS OF MAKING AND USING THE SAME Life Technologies Corporation (US) 2012-10-04 US claimed
US-20120135472-A1 HOT-START PCR BASED ON THE PROTEIN TRANS-SPLICING OF NANOARCHAEUM EQUITANS DNA POLYMERASE Research & Business Foundation Sungkyunkwan University (KR) 2012-05-31 US claimed
US-7915392-B2 5-bromo-2′-deoxy-uridine labeled nucleotide triphosphates and nucleic acid probes and methods of making and using the same Life Technologies Corporation (US) 2011-03-29 US claimed
US-20100015670-A1 METHOD OF MODIFYING NUCLEOTIDE CHAIN PANASONIC CORPORATION (JP) 2010-01-21 US claimed
EP-0724647-A4 NUCLEIC ACID LIGANDS AND IMPROVED METHODS FOR PRODUCING THE SAME GILEAD SCIENCES INC (US) 2003-09-17 EP claimed
WO-2003055898-A1 ENZYMATIC REDOX LABELLING OF NUCLEIC ACIDS UNISEARCH LIMITED (AU) 2003-07-10 WO claimed
US-6589742-B2 Producing single stranded amplicon species for detection, using asymmetrical amplification rather than heat or chemical denaturation NANOGEN, INC. 2003-07-08 US claimed
EP-1025115-B1 NOVEL NUCLEOSIDE OR NUCLEOTIDE FLUORESCENT CONJUGATES, PREPARATION METHOD AND USES CIS BIO INT (FR) 2003-06-04 EP claimed
US-6531302-B1 Using primer pair sets anchored to a microarray through capture sites or through a branched primer pair moiety; allows for simultaneous multiplex capture, amplification, and detection of a target nucleic acid NANOGEN/BECTON DICKINSON PARTNERSHIP 2003-03-11 US claimed
WO-2000060919-B1 ANCHORED STRAND DISPLACEMENT AMPLIFICATION ON AN ELECTRONICALLY ADDRESSABLE MICROCHIP NANOGEN BECTON DICKINSON PARTN (US) 2002-01-31 WO claimed
US-6340747-B1 COMPLEXED TO RARE EARTH METAL CRYPTATE LABEL; DETECTION AND ISOLATION OF NUCLEIC ACIDS CIS BIO INTERNATIONAL (FR) 2002-01-22 US claimed
US-6063604-A SEPARATION OF TARGET NUCLEOTIDE SEQUENCE FOUND WITHIN A SINGLE-STRANDED POLYNUCLEOTIDE; PROVIDING A REACTION MIXTURE, SEPARATING NUCLEOTIDE SEQUENCES, ALLOWING HYBRIDIZATION, PRIMER EXTENSION AND BREAKING, AMPLIFY NUCLEOTIDES MOLECULAR BIOLOGY RESOURCES, INC. (US) 2000-05-16 US claimed
EP-0724647-A1 NUCLEIC ACID LIGANDS AND IMPROVED METHODS FOR PRODUCING THE SAME NeXstar Pharmaceuticals, Inc. (US) 1996-08-07 EP claimed
WO-1995007364-A1 NUCLEIC ACID LIGANDS AND IMPROVED METHODS FOR PRODUCING THE SAME NEXSTAR PHARMACEUTICALS, INC. (US) 1995-03-16 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120252030-A1 5-BROMO-2'-DEOXY-URIDINE LABELED NUCLEOTIDE TRIPHOSPHATES AND NUCLEIC ACID PROBES AND METHODS OF MAKING AND USING THE SAME DUT, PCNA, TK1 DUT 1/4885P2RY2 725/4885P2RY4 636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.