Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.74 |
| ▸ | P2RY2 | P41231 | 15/20 | 0.67 |
| ▸ | P2RY4 | P51582 | 11/20 | 0.67 |
| ▸ | P2RY6 | Q15077 | 8/20 | 0.67 |
| ▸ | POLA1 | P09884 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20798009 | 0.99 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| SCHEMBL27554036 | 0.99 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| SCHEMBL8003 | 0.99 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| SCHEMBL12729520 | 0.99 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| SCHEMBL48209 | 0.99 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| SCHEMBL20074354 | 0.99 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| SCHEMBL16633413 | 0.99 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| SCHEMBL2349191 | 0.99 | DUT (0.75) | DUTP2RY2P2RY4P2RY6POLA1 | |
| Water SCHEMBL3961110 | 0.98 | DUT (0.74) | DUTP2RY2P2RY4P2RY6POLA1 | |
| Bromide SCHEMBL18112592 | 0.98 | DUT (0.74) | DUTP2RY2P2RY4P2RY6POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3230524-B2 | — | — | 2001-11-19 | — | — | JP | claimed |
| EP-0447442-B1 | METHOD FOR POLYMERASE ACTIVITY DETERMINATION | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1994-09-21 | — | — | EP | claimed |
| EP-0447442-A1 | METHOD FOR POLYMERASE ACTIVITY DETERMINATION. | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1991-09-25 | — | — | EP | claimed |
| WO-1990006320-A1 | SUBSTRATE FOR POLYMERASE ACTIVITY DETERMINATION | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1990-06-14 | — | — | WO | claimed |
| WO-1990006373-A1 | METHOD FOR POLYMERASE ACTIVITY DETERMINATION | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1990-06-14 | — | — | WO | claimed |
| EP-0447442-B1 | METHOD FOR POLYMERASE ACTIVITY DETERMINATION | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1994-09-21 | — | — | EP | disclosed |
| EP-0447442-A1 | METHOD FOR POLYMERASE ACTIVITY DETERMINATION. | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1991-09-25 | — | — | EP | disclosed |
| WO-1990006373-A1 | METHOD FOR POLYMERASE ACTIVITY DETERMINATION | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1990-06-14 | — | — | WO | disclosed |
| WO-1990006320-A1 | SUBSTRATE FOR POLYMERASE ACTIVITY DETERMINATION | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1990-06-14 | — | — | WO | disclosed |
| WO-1990006320-A1 | SUBSTRATE FOR POLYMERASE ACTIVITY DETERMINATION | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1990-06-14 | — | — | WO | disclosed |