SCHEMBL12729520

SCHEMBL12729520

O=c1ccn(C2CC(O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1

nearest known ligand 0.75

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.75
P2RY2 P41231 15/20 0.68
P2RY4 P51582 10/20 0.68
P2RY6 Q15077 8/20 0.68
POLA1 P09884 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2349191 1.00 DUT (0.75) DUTP2RY2P2RY4P2RY6POLA1
SCHEMBL20798009 1.00 DUT (0.75) DUTP2RY2P2RY4P2RY6POLA1
SCHEMBL27554036 1.00 DUT (0.75) DUTP2RY2P2RY4P2RY6POLA1
SCHEMBL20074354 1.00 DUT (0.75) DUTP2RY2P2RY4P2RY6POLA1
SCHEMBL48209 1.00 DUT (0.75) DUTP2RY2P2RY4P2RY6POLA1
SCHEMBL16633413 1.00 DUT (0.75) DUTP2RY2P2RY4P2RY6POLA1
SCHEMBL8003 1.00 DUT (0.75) DUTP2RY2P2RY4P2RY6POLA1
Water SCHEMBL3961110 0.99 DUT (0.74) DUTP2RY2P2RY4P2RY6POLA1
Bromide SCHEMBL18112592 0.99 DUT (0.74) DUTP2RY2P2RY4P2RY6POLA1
Iodide SCHEMBL7941539 0.99 DUT (0.74) DUTP2RY2P2RY4P2RY6POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160168636-A1 NUCLEOTIDE ANALOGS HELICOS BIOSCIENCES CORPORATION 2016-06-16 US disclosed
US-20160168636-A1 NUCLEOTIDE ANALOGS HELICOS BIOSCIENCES CORPORATION 2016-06-16 US disclosed
US-9163053-B2 Nucleotide analogs FLUIDIGM CORPORATION (US) 2015-10-20 US disclosed
US-9163053-B2 Nucleotide analogs FLUIDIGM CORPORATION (US) 2015-10-20 US disclosed
US-8680062-B2 System for delivering therapeutic agents into living cells and cells nuclei Deliversir Ltd. (IL) 2014-03-25 US disclosed
US-8680062-B2 System for delivering therapeutic agents into living cells and cells nuclei Deliversir Ltd. (IL) 2014-03-25 US disclosed
US-20110081647-A1 NUCLEOTIDE ANALOGS HELICOS BIOSCIENCES CORPORATION (US) 2011-04-07 US disclosed
US-20110081647-A1 NUCLEOTIDE ANALOGS HELICOS BIOSCIENCES CORPORATION (US) 2011-04-07 US disclosed
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei SEGEV LABORATORIES LIMITED (IL) 2008-01-03 US disclosed
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei SEGEV LABORATORIES LIMITED (IL) 2008-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110081647-A1 NUCLEOTIDE ANALOGS DUT, NT5C2, NUDT21 DUT 1/4885P2RY2 249/4885P2RY4 148/4885
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei RCC1, NUMA1, ACIN1 DUT 269/4885P2RY2 4592/4885P2RY4 4660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.