SCHEMBL23498992

SCHEMBL23498992

c1ccc(CN(Cc2ccccc2)CC2CCO2)cc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
OXTR P30559 6/20 0.41
AVPR1A P37288 6/20 0.41
KDM4E B2RXH2 2/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 3/20 0.40
LMNA P02545 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
OPRM1 P35372 1/20 0.39
OPRD1 P41143 1/20 0.39
OPRK1 P41145 1/20 0.39
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23498743 1.00 OXTR (0.41) OXTRAVPR1AKDM4EHSD17B10MEN1
SCHEMBL28473802 0.91 OXTR (0.50) OXTRAVPR1AKDM4EMEN1KMT2A
SCHEMBL28473805 0.91 OXTR (0.50) OXTRAVPR1AKDM4EMEN1KMT2A
SCHEMBL28476929 0.91 OXTR (0.50) OXTRAVPR1AKDM4EMEN1KMT2A
SCHEMBL15050220 0.85 LMNA (0.44) KDM4EHSD17B10MEN1KMT2AALDH1A1
SCHEMBL1323564 0.85 LMNA (0.44) KDM4EHSD17B10MEN1KMT2AALDH1A1
SCHEMBL13737372 0.85 LMNA (0.44) KDM4EHSD17B10MEN1KMT2AALDH1A1
SCHEMBL1472102 0.81 LMNA (0.44) KDM4EHSD17B10MEN1KMT2AALDH1A1
SCHEMBL22204407 0.75 KDM4E (0.46) KDM4EL3MBTL1OPRM1TSHR
SCHEMBL3385520 0.75 KCNH3 (0.42) KDM4EHSD17B10MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473267-B2 Process and intermediate for the preparation of oxetan-2-yl-methanamine ELI LILLY AND COMPANY (US) 2025-11-18 US disclosed
EP-4073051-B1 PROCESS AND INTERMEDIATE FOR THE PREPARATION OF OXETAN-2-YLMETHANAMINE LILLY CO ELI (US) 2024-02-07 EP disclosed
US-20230013840-A1 PROCESS AND INTERMEDIATE FOR THE PREPARATION OF OXETAN-2-YL-METHANAMINE ELI LILLY AND COMPANY 2023-01-19 US disclosed
US-20230013840-A1 PROCESS AND INTERMEDIATE FOR THE PREPARATION OF OXETAN-2-YL-METHANAMINE ELI LILLY AND COMPANY 2023-01-19 US disclosed
EP-4073051-A1 PROCESS AND INTERMEDIATE FOR THE PREPARATION OF OXETAN-2-YLMETHANAMINE Eli Lilly and Company (US) 2022-10-19 EP disclosed
CN-114728923-A Process and intermediates for the preparation of oxetan-2-ylmethylamines 伊莱利利公司 2022-07-08 CN disclosed
WO-2021118906-A1 PROCESS AND INTERMEDIATE FOR THE PREPARATION OF OXETAN-2-YLMETHANAMINE ELI LILLY AND COMPANY (US) 2021-06-17 WO disclosed
WO-2021118906-A1 PROCESS AND INTERMEDIATE FOR THE PREPARATION OF OXETAN-2-YLMETHANAMINE ELI LILLY AND COMPANY (US) 2021-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12473267-B2 Process and intermediate for the preparation of oxetan-2-yl-methanamine CYP11B2, CYP11B1, MSMO1 OXTR 4/4885AVPR1A 137/4885KDM4E 1293/4885
US-20230013840-A1 PROCESS AND INTERMEDIATE FOR THE PREPARATION OF OXETAN-2-YL-METHANAMINE CYP11B2, CYP11B1, MSMO1 OXTR 4/4885AVPR1A 137/4885KDM4E 1293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.