Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933965 | 1.00 | PKM (0.44) | PKMABL1SRCHKDC1SMN1; SMN2 | |
| SCHEMBL29934040 | 0.88 | POLB (0.44) | PKMSMN1; SMN2MAPTHTTMAPK1 | |
| SCHEMBL23501594 | 0.88 | POLB (0.44) | PKMSMN1; SMN2MAPTHTTMAPK1 | |
| SCHEMBL28884685 | 0.82 | ABL1 (0.44) | ABL1SRCHKDC1HIF1ACA1 | |
| SCHEMBL29933997 | 0.78 | PKM (0.43) | PKMSMN1; SMN2MAPTHTTMAPK1 | |
| SCHEMBL29933987 | 0.76 | TAS1R3 (0.47) | KDM4EMEN1KMT2A | |
| SCHEMBL23501683 | 0.76 | ATM (0.40) | ABL1SRCHKDC1HIF1ACA1 | |
| SCHEMBL23501655 | 0.76 | HDAC8 (0.48) | PKMSMN1; SMN2MAPTHTTMAPK1 | |
| SCHEMBL29934020 | 0.76 | ATM (0.40) | ABL1SRCHKDC1HIF1ACA1 | |
| SCHEMBL29934010 | 0.76 | HDAC8 (0.48) | PKMSMN1; SMN2MAPTHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |
| WO-2021117846-A1 | COMPOUND SERVING AS PDGF RECEPTOR KINASE INHIBITOR, AND COMPOSITION | 日本新薬株式会社 | 2021-06-17 | — | — | WO | disclosed |