Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 8/20 | 0.46 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CTSB | P07858 | 4/20 | 0.46 |
| ▸ | CTSV | O60911 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23506241 | 0.96 | CTSK (0.50) | CTSKTAS1R3TAS1R1CTSLCTSB | |
| SCHEMBL21702267 | 0.92 | CTSL (0.46) | CTSKCTSLCTSSCTSB | |
| SCHEMBL21702035 | 0.90 | CTSL (0.48) | CTSKCTSLCTSSCTSB | |
| SCHEMBL26494831 | 0.90 | CTSL (0.48) | CTSKCTSLCTSSCTSB | |
| SCHEMBL23506458 | 0.90 | CTSK (0.50) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL23711638 | 0.90 | CTSK (0.50) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL23506297 | 0.88 | CTSK (0.51) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL26494879 | 0.88 | CAPN1 (0.46) | CTSKCTSLCTSSCTSB | |
| SCHEMBL26494839 | 0.87 | CTSL (0.42) | CTSKCTSLCTSSCTSB | |
| SCHEMBL26495102 | 0.87 | CTSL (0.40) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133600-A1 | PHARMACEUTICAL USE OF KETOAMIDE-BASED COMPOUND | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2023-05-04 | — | — | US | disclosed |
| EP-3835296-A1 | KETOAMIDE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133600-A1 | PHARMACEUTICAL USE OF KETOAMIDE-BASED COMPOUND | CTSL, CTSV, CTSS | CTSK 13/4885TAS1R3 2190/4885TAS1R1 2163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.