Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23506431 | 0.87 | CTSL (0.39) | ALDH1A1GRNSORT1 | |
| SCHEMBL21702102 | 0.84 | CTSL (0.35) | — | |
| SCHEMBL23506361 | 0.83 | MMP13 (0.37) | ALDH1A1GRNSORT1 | |
| SCHEMBL23711130 | 0.81 | CTSL (0.43) | — | |
| SCHEMBL21702301 | 0.81 | CTSL (0.43) | — | |
| SCHEMBL21702106 | 0.80 | RAB9A (0.41) | ALDH1A1 | |
| SCHEMBL23506275 | 0.80 | RAB9A (0.41) | ALDH1A1 | |
| SCHEMBL23506336 | 0.79 | CTSL (0.40) | — | |
| SCHEMBL23506556 | 0.79 | — | — | |
| SCHEMBL23506413 | 0.78 | CTSS (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3835296-A1 | KETOAMIDE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-06-16 | — | — | EP | disclosed |