Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Catechol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | CA2 | P00918 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | CA4 | P22748 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 3/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | EGFR | P00533 | 2/20 | 0.67 |
| ▸ | FYN | P06241 | 2/20 | 0.67 |
| ▸ | MMP9 | P14780 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | CA3 | P07451 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Catechol SCHEMBL29652083 | 1.00 | KDM4E (0.67) | KDM4EALDH1A1CA2SMN1; SMN2HPGD | |
| Catechol SCHEMBL1143838 | 1.00 | KDM4E (0.67) | KDM4EALDH1A1CA2SMN1; SMN2HPGD | |
| Catechol SCHEMBL27989011 | 1.00 | KDM4E (0.67) | KDM4EALDH1A1CA2SMN1; SMN2HPGD | |
| Catechol SCHEMBL23111816 | 0.97 | ALDH1A1 (0.62) | KDM4EALDH1A1CA2SMN1; SMN2HPGD | |
| Catechol SCHEMBL11405646 | 0.97 | ALDH1A1 (0.62) | KDM4EALDH1A1CA2SMN1; SMN2HPGD | |
| Catechol SCHEMBL11778548 | 0.88 | SMN1; SMN2 (0.59) | KDM4EALDH1A1CA2SMN1; SMN2HPGD | |
| Catechol SCHEMBL10535949 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1CA2SMN1; SMN2HPGD | |
| Catechol SCHEMBL1491270 | 0.84 | ALDH1A1 (0.62) | KDM4EALDH1A1CA2SMN1; SMN2HPGD | |
| Catechol SCHEMBL1143840 | 0.83 | CA2 (0.53) | KDM4EALDH1A1CA2SMN1; SMN2HPGD | |
| Trifluoromethanesulfonic Acid SCHEMBL1712877 | 0.83 | CA2 (0.53) | KDM4EALDH1A1CA2SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025123045-A1 | PREDICTIVE AND DIAGNOSTIC SCREENING METHODS FOR ENDOMETRIAL CANCER | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2025-06-12 | — | — | WO | claimed |
| CN-119695238-A | Battery cell | 广州天赐高新材料股份有限公司 | 2025-03-25 | — | — | CN | claimed |
| EP-4457513-A1 | COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE | Société des Produits Nestlé S.A. (CH) | 2024-11-06 | — | — | EP | claimed |
| EP-4424365-A2 | PET FOOD COMPOSITIONS | Hill's Pet Nutrition, Inc. (US) | 2024-09-04 | — | — | EP | claimed |
| EP-4017281-B1 | PET FOOD COMPOSITIONS | HILLS PET NUTRITION INC (US) | 2024-08-28 | — | — | EP | claimed |
| CN-118435054-A | Compositions and methods for diagnosing and treating chronic kidney disease | 雀巢产品有限公司 | 2024-08-02 | — | — | CN | claimed |
| US-12050228-B2 | Automated sample quality assessment | METABOLON, INC. (US) | 2024-07-30 | — | — | US | claimed |
| EP-3321686-B1 | BIOMARKERS RELATED TO INSULIN RESISTANCE PROGRESSION AND METHODS USING THE SAME | METABOLON INC (US) | 2024-03-13 | — | — | EP | claimed |
| CN-117477033-A | Electrolyte and battery | 广州天赐高新材料股份有限公司 | 2024-01-30 | — | — | CN | claimed |
| US-20230375534-A1 | MEANS AND METHODS TO DIAGNOSE GUT FLORA DYSBIOSIS AND INFLAMMATION | VIB VZW (BE) | 2023-11-23 | — | — | US | claimed |
| EP-2914962-A1 | BIOMARKERS OF MULTIPLE MYELOMA DEVELOPMENT AND PROGRESSION | Ospedale San Raffaele S.r.l. (IT) | 2015-09-09 | — | — | EP | claimed |
| US-20150065366-A1 | Biomarkers for Bladder Cancer and Methods Using the Same | METABOLON, INC. | 2015-03-05 | — | — | US | claimed |
| CN-104204798-A | Biomarkers for bladder cancer and methods using the same | METABOLON INC | 2014-12-10 | — | — | CN | claimed |
| EP-2776832-A1 | BIOMARKERS FOR BLADDER CANCER AND METHODS USING THE SAME | Metabolon, Inc. (US) | 2014-09-17 | — | — | EP | claimed |
| WO-2014120449-A1 | BIOMARKERS RELATED TO INSULIN RESISTANCE PROGRESSION AND METHODS USING THE SAME | METABOLON, INC. (US) | 2014-08-07 | — | — | WO | claimed |
| WO-2014068144-A1 | BIOMARKERS OF MULTIPLE MYELOMA DEVELOPMENT AND PROGRESSION | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2014-05-08 | — | — | WO | claimed |
| US-8658351-B2 | Determining liver toxicity of an agent using metabolite biomarkers | METABOLON, INC. (US) | 2014-02-25 | — | — | US | claimed |
| WO-2013070839-A1 | BIOMARKERS FOR BLADDER CANCER AND METHODS USING THE SAME | METABOLON, INC. (US) | 2013-05-16 | — | — | WO | claimed |
| US-20120122981-A1 | Biomarkers Related to Insulin Resistance and Methods using the Same | METABOLON, INC. | 2012-05-17 | — | — | US | claimed |
| US-4290975-A | N-Sulfonyl amine-mediated sulfamation of amines | NUTRASWEET COMPANY THE | 1981-09-22 | — | — | US | claimed |