Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 6/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.44 |
| ▸ | ECE1 | P42892 | 5/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | CPA2 | P48052 | 1/20 | 0.43 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23515632 | 0.92 | MME (0.51) | ACE2MMEANPEPECE1 | |
| SCHEMBL26122670 | 0.79 | ACE2 (0.50) | ACE2MMEANPEPECE1 | |
| SCHEMBL6923615 | 0.78 | ACE2 (0.58) | ACE2MMEECE1MMP1MMP3 | |
| SCHEMBL23501480 | 0.76 | MME (0.52) | ACE2MMEANPEPECE1 | |
| SCHEMBL24991304 | 0.75 | ACE2 (0.69) | ACE2MMEECE1MMP1MMP3 | |
| SCHEMBL7613146 | 0.75 | ACE2 (0.69) | ACE2MMEECE1MMP1MMP3 | |
| SCHEMBL1764208 | 0.75 | ACE2 (0.69) | ACE2MMEECE1MMP1MMP3 | |
| SCHEMBL7613489 | 0.75 | ACE2 (0.69) | ACE2MMEECE1MMP1MMP3 | |
| SCHEMBL1764061 | 0.75 | ACE2 (0.49) | ACE2MMEANPEPECE1 | |
| SCHEMBL6923553 | 0.72 | ECE1 (0.68) | ACE2MMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021116617-A1 | PROCESS FOR INDUSTRIAL PREPARATION OF THE DISODIUM SALT OF ((2S)-3-([1,1'-BIPHENYL]-4-YL)-2-((HYDROXY((1R)-1-(((1-(ISOBUTYRYLOXY)ETHOXY)CARBONYL)AMINO)ETHYL)PHOSPHORYL)METHYL)PROPANOYL)-L-ALANINE | PHARMALEADS (FR) | 2021-06-17 | — | — | WO | disclosed |