SCHEMBL235157

SCHEMBL235157

[C]1=C(C2CCCC2)C=CC1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3693133 0.98 CYP11B2 (0.31)
SCHEMBL218979 0.98 CYP11B2 (0.31)
SCHEMBL2971884 0.95
SCHEMBL217251 0.90
SCHEMBL4537045 0.83
SCHEMBL2323262 0.76
SCHEMBL481596 0.74
SCHEMBL8122799 0.71
SCHEMBL4542108 0.64 DAO (0.31)
SCHEMBL217366 0.61 HTR3A (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104159929-A Supported composite metallocene catalyst, method for preparing the same, and method for preparing polyolefin using the same SK INNOVATION CO LTD 2014-11-19 CN claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-20030207757-A1 Catalyst composition comprising metallocene compound having bulky cycloalkyl-substituted cyclopentadienyl ligand, and process for olefin polymerization using the same DAELIM INDUSTRIES CO., LTD. (KR) 2003-11-06 US claimed
CN-112689634-B SMAD3 inhibitors 莫扎制药有限公司 2024-07-16 CN disclosed
CN-118355029-A Methods of treating diffuse large B-cell lymphomas using anti-CD 79B immunoconjugates 基因泰克公司 2024-07-16 CN disclosed
US-20240226342-A1 REACTIVE OXYGEN SPECIES IMAGING AGENTS WASHINGTON UNIVERSITY (US) 2024-07-11 US disclosed
US-12016842-B2 Methods of using anti-CD79b immunoconjugates GENENTECH, INC. (US) 2024-06-25 US disclosed
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 CN disclosed
EP-4380978-A1 METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA Genentech, Inc. (US) 2024-06-12 EP disclosed
US-11998584-B2 Conjugate of a tubulysin analog with branched linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2024-06-04 US disclosed
US-20240179825-A1 SYSTEMS AND METHODS FOR NONEQUILIBRIUM PLASMAS WASHINGTON UNIVERSITY 2024-05-30 US disclosed
US-6258744-B1 OLEFIN POLYMERIZATION CATALYST BAYER AKTIENGESELLSCHAFT (DE) 2001-07-10 US disclosed
EP-1066296-A1 NOVEL DENDRIMER COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS CATALYSTS Bayer Aktiengesellschaft (DE) 2001-01-10 EP disclosed
EP-1063243-A2 Olefin polymerization process and catalyst system therefor BAYER AG (DE) 2000-12-27 EP disclosed
CN-1278265-A Process for preparing fulvene metal complexes BAYER AG (DE) 2000-12-27 CN disclosed
EP-1028968-A1 METHOD FOR PRODUCING FULVENE METAL COMPLEXES BAYER AG (DE) 2000-08-23 EP disclosed
CN-1246486-A Catalyst system based on fulvene metal compound BAYER AG (DE) 2000-03-08 CN disclosed
EP-0982319-A2 Catalyst system based on fulvene-cyclopentadienyl-metal complexes Bayer Aktiengesellschaft (DE) 2000-03-01 EP disclosed
WO-1999048898-A1 NOVEL DENDRIMER COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS CATALYSTS BAYER AKTIENGESELLSCHAFT (DE) 1999-09-30 WO disclosed
WO-1999024445-A1 METHOD FOR PRODUCING FULVENE METAL COMPLEXES BAYER AKTIENGESELLSCHAFT (DE) 1999-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226342-A1 REACTIVE OXYGEN SPECIES IMAGING AGENTS ROS1, NOX4, CYBB MAOA 542/4885MAOB 319/4885
US-12016842-B2 Methods of using anti-CD79b immunoconjugates CD79B, CD99, BCL6 MAOA 4021/4885MAOB 1050/4885
US-11998584-B2 Conjugate of a tubulysin analog with branched linkers TEKT1, TEK, CD2BP2 MAOA 4139/4885MAOB 4138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.