SCHEMBL23519082

SCHEMBL23519082

O=C(O)C(F)(F)Oc1ccc(Cl)c(F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.48
PPARG P37231 1/20 0.48
FFAR4 Q5NUL3 5/20 0.46
HRH3 Q9Y5N1 1/20 0.41
CHRNA3 P32297 1/20 0.41
SCN5A Q14524 2/20 0.40
FFAR1 O14842 2/20 0.40
CYP2C9 P11712 1/20 0.40
CYP3A4 P08684 2/20 0.39
KCNH2 Q12809 1/20 0.39
CACNA1C Q13936 1/20 0.39
SLC6A4 P31645 1/20 0.39
ERCC5 P28715 1/20 0.39
FEN1 P39748 1/20 0.39
ATF4 P18848 4/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23519088 0.85 AKR1C2 (0.40) PPARAFFAR4SCN5AFFAR1CYP2C9
SCHEMBL23519097 0.84 CES2 (0.41) PPARAFFAR4FFAR1CYP3A4MEN1
SCHEMBL31117868 0.83 PPARA (0.60) PPARAPPARGFFAR4CYP2C9CYP3A4
SCHEMBL23519092 0.83 MCL1 (0.54) PPARAFFAR4SCN5AFFAR1CYP3A4
SCHEMBL23519100 0.83 PPARG (0.52) PPARAPPARGMAPT
SCHEMBL3371724 0.83 PPARA (0.60) PPARAPPARGFFAR4CYP2C9CYP3A4
Trifluoroacetic Acid SCHEMBL28514921 0.83 PPARA (0.46) PPARAPPARGFFAR4HRH3CHRNA3
SCHEMBL11065683 0.80 FFAR4 (0.48) PPARAPPARGFFAR4SCN5AFFAR1
SCHEMBL23519083 0.78 PPARA (0.61) PPARAPPARGCYP3A4MEN1CYP1A2
SCHEMBL23518992 0.78 EPHX2 (0.54) PPARAFFAR4FFAR1MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210179554-A1 ONIUM SALT COMPOUND, CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210179554-A1 ONIUM SALT COMPOUND, CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SLC6A5, LIFR, SLC6A9 PPARA 3267/4885PPARG 3765/4885FFAR4 2411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.