SCHEMBL23520286

SCHEMBL23520286

C=C1c2ccccc2N2CCCC12CCC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30257936 0.69 ALDH1A1 (0.37) MEN1ALDH1A1KMT2A
SCHEMBL23497804 0.68 ALDH1A1 (0.33) MEN1ALDH1A1KMT2A
SCHEMBL29932206 0.68 ALDH1A1 (0.33) MEN1ALDH1A1KMT2A
SCHEMBL13330404 0.65 OPRM1 (0.39)
SCHEMBL30829193 0.61 SLC6A4 (0.41) MEN1KMT2A
SCHEMBL6441060 0.60 HDAC4 (0.36) MEN1ALDH1A1KMT2A
SCHEMBL28120389 0.59 SIGMAR1 (0.38)
Water SCHEMBL28199644 0.58 SIGMAR1 (0.37)
SCHEMBL30228535 0.57 FFAR1 (0.41) MEN1ALDH1A1KMT2A
SCHEMBL8416690 0.57 OPRM1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021116686-A1 METHYL 2-ALLYL-1 -METHYL-3-OXOINDOLINE-2-CARBOXYLATE AND 9A-ALLYL-1,2,3,9A-TETRAHYDRO-9H-PYRROLO[1,2-A]INDOL-9-ONE DERIVATIVES AND RELATED COMPOUNDS FOR USE AS FLUORESCENT MARKERS FOR LABELLING OF DRUGS, AMINO ACIDS AN PROTEINS UNIVERSITY OF LANCASTER (GB) 2021-06-17 WO disclosed