Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695050 | 0.76 | HTR7 (0.38) | OPRM1OPRD1OPRK1OPRL1HTR1A | |
| SCHEMBL6695054 | 0.76 | HTR7 (0.38) | OPRM1OPRD1OPRK1OPRL1HTR1A | |
| SCHEMBL604857 | 0.75 | SLC6A3 (0.40) | HTR1AALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL604859 | 0.75 | SLC6A3 (0.40) | HTR1AALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL22245613 | 0.67 | SMN1; SMN2 (0.40) | ADRA1BHTR1ASMN1; SMN2FFAR1ALDH1A1 | |
| SCHEMBL23555148 | 0.65 | ADRB1 (0.50) | ADRA1BHTR1ASMN1; SMN2ADRB1ALDH1A1 | |
| SCHEMBL3436331 | 0.65 | ADRB1 (0.50) | ADRA1BHTR1ASMN1; SMN2ADRB1ALDH1A1 | |
| SCHEMBL29908655 | 0.65 | CFB (0.39) | OPRM1OPRD1OPRL1SMN1; SMN2FFAR1 | |
| SCHEMBL606912 | 0.65 | CFB (0.39) | OPRM1OPRD1OPRL1SMN1; SMN2FFAR1 | |
| SCHEMBL246216 | 0.65 | CFB (0.39) | OPRM1OPRD1OPRL1SMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919456-B2 | Catalytic compositions and methods for asymmetric aldol reactions | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2005-07-19 | — | — | US | disclosed |
| EP-1409122-A2 | CATALYTIC COMPOSITIONS AND METHODS FOR ASYMMETRIC ALDOL REACTIONS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2004-04-21 | — | — | EP | disclosed |
| US-20040019239-A1 | Catalytic compositions and methods for asymmetric aldol reactions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-01-29 | — | — | US | disclosed |
| US-6610889-B2 | Using organometallic complex catalyst | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2003-08-26 | — | — | US | disclosed |
| US-20020147367-A1 | Catalytic compositions and methods for asymmetric aldol reactions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-10-10 | — | — | US | disclosed |
| WO-2002041984-A2 | CATALYTIC COMPOSITIONS AND METHODS FOR ASYMMETRIC ALDOL REACTIONS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2002-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147367-A1 | Catalytic compositions and methods for asymmetric aldol reactions | ADH1C, ADH5, ADH1A | HDAC4 3760/4885OPRM1 1540/4885OPRD1 1805/4885 |
| US-20040019239-A1 | Catalytic compositions and methods for asymmetric aldol reactions | ADH1C, ADH5, ADH1A | HDAC4 3760/4885OPRM1 1540/4885OPRD1 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.